三叉神经痛神经脱髓鞘变程度的定量分析  

Quantitative analysis on the demyelination degree of trigeminal neuralgia nerve branches

作　　者：孙卫革[1] 刘向辉[1] 张玲[1] 周红文[1] 姜晓钟[2] 赵云富[2] 黄建涛[2] 

机构地区：[1]解放军第八一医院口腔科,江苏南京210002 [2]第二军医大学附属长征医院口腔科,上海200003

出　　处：《医学研究生学报》2004年第2期142-143,147,共3页Journal of Medical Postgraduates

基　　金：军队医药卫生科研基金资助项目 (批准号 :98M0 84)

摘　　要：目的 :研究三叉神经脱髓鞘变程度与三叉神经痛的关系。　方法 :选 6例下齿槽神经痛患者 ,取其患支下齿槽神经、颏神经 ,并取其未发病的舌神经为自身对照 ;选择 4例无三叉神经痛患者的下齿槽神经作为正常对照 ,利用图像分析系统测量并用统计学的方法定量分析比较四组神经脱髓鞘变的程度。　结果 :三叉神经痛患者的患支神经的脱髓鞘变程度与正常对照神经相比差异有显著性意义 (P <0 .0 5 )。　结论Objective:To study the relation between demyelination and trigeminal neuralgia. Methods:Cut the diseased inferior alveolar nerve branches and chin nerve branches from 6 patients suffering from trigeminal neuralgia during operation. Cut the normal tongue nerve as the self control from them, and inferior alveolar nerve of 4 cases of non-trigeminal neuralgia as control . To apply the image analysis system to measure,then quantitatively analysis by statistical method and compare the degree on demyelination of the 4 groups of nerve branches. Results:Difference between the diseased nerve branches and the normal ones of trigeminal neuralgia is significant(P<0.05).Difference between the nerve branches of self control and those of normal control is not significant(P>0.05). Conclusion:The degree on demyelination of peripheral nerve branches is relevant to trigeminal neuralgia.

关 键 词：三叉神经痛 脱髓鞘变 定量分析 

分 类 号：R745.11[医药卫生—神经病学与精神病学]