性别对肺癌术后预后的影响  

Sex effect on prognosis after lung cancer operation

作　　者：施民新[1] 许广照[1] 高俊[1] 樊天友[1] 王强[1] 

机构地区：[1]江苏省南通市肿瘤医院胸外科,江苏南通226361

出　　处：《现代肿瘤医学》2004年第1期36-37,共2页Journal of Modern Oncology

摘　　要：目的　探讨女性非小细胞肺癌各种特征和手术治疗后生存率 ,性别对肺癌术后预后的影响。方法回顾性分析我院 1980～ 2 0 0 0年非小细胞肺癌手术治疗 12 4 2病例 ,其中女性病例 337例 ( 2 7.1% ) ,对患者性别、年龄、组织学、肿瘤直径、位置、吸咽习惯、术前、术后CEA、Brinkmanindex可能影响生存率的因素进行了分析。结果　女性病人有如下特征 :年龄相对低 ,女∶男 =6 2 .5∶6 4 .1;腺癌发生率高 ,女∶男 =86 .0 %∶4 8.3% ;肿瘤直径小 ,女∶男 =32 .7mm∶38.3mm ;周围型更常见 ,女∶男 =71.8%∶5 0 .6 % ;有吸咽史 6 86例 ,女∶男=12 .8%∶91.4 % ;完全切除相对低 ,女∶男 =79.6 %∶85 .2 %。相同条件情况下 ,女性完全切除后的生存率比男性长。女性术后癌胚抗原 (CEA)阴性对预后的预测相对男性更有意义。然而女性术后CEA阳性则反之。相同条件下 ,女性≥ 6 0岁生存率比男性长 ,而 <6 0岁的反之。结论　一旦肿瘤完全切除 ,女性生存率较长 ,部分可能受预期寿命长影响有关。然而 ,女性非小细胞肺癌外侵率高 ,切除率相对男性病人低。Objective Approach varieties of features in female non-small cell lung cancer,living rate after operation and the effect of sex on prognosis.Methods Review and analyse 1242 cases of these kinds of operations between 1980 and 2000 in our hospital;among them,337 female cases(27.1%) analyse patients'sex,age,histology,tumour diameter,place,smoking habit and factors CEA?Brinkman index before and after operation.Results Female patients have the following features:female patients were younger than male,female∶male=62.5∶64.1 more adenoma,female∶male=86.0%∶48.3% short tumour diameter,female∶male=32.7mm∶38.3mm peripheral models more common,female∶male=71.8%∶50.6%,686 patients ever smoking,female∶male=12.8%∶91.4%;low rate of cutting tumour completely,female∶male 79.6%∶85.2% female patients live longer than male after cutting tumour completely,negative of female embryo antigen(CEA) was more meaningful in forecasting of prognosis,while opposite if positive in the same condition;female patients over 60 years old live longer than male,while female under 60 years old opposite in the same condition. Conclusion Once tumour is cut completely,female live longer than male;part of possible reasons are long life;however,they have high rate of invasion and the cutting rate is lower than male.

关 键 词：性别 手术 非小细胞肺癌 肿瘤 治疗 临床资料 

分 类 号：R734.2[医药卫生—肿瘤]