Effect of Repetitive Bleeding on NADH-Cytochrome b_5 Methemoglobin Reductase Activity and Molybdenum Content in Erythrocytes of Rats  

作　　者：YANG YUAN WANG FAN Li GUANG-SHENG AND KANG DE-REN (Gastroenterological Center, Hospital No. 222, People,s Liberation Army,Jilin 132011, China Department of Pathology, Institute of Preclinical Science, Norman Bethune University of Medical Sciences,Ch 

出　　处：《Biomedical and Environmental Sciences》1996年第4期393-398,共6页生物医学与环境科学（英文版）

摘　　要：Reticulocytosls in rats was induced by repetitive bleeding. Both the in vitro and the in vivo studies showed that the detected reductive speed of methemoglobin of the bleeding group was faster than that of the control group at all time intervals. At the same time, the NADH-cytochrome b5 methemoglobin reductase activity and the molybdenum content in erythrocytes of the bleeding group were significantly increased. Regressional analysis showed that there was a significantly positive correlation between the enzyme activity and the molybdenum content. It is proposed that molybdenum might be required for the enzyme activityReticulocytosls in rats was induced by repetitive bleeding. Both the in vitro and the in vivo studies showed that the detected reductive speed of methemoglobin of the bleeding group was faster than that of the control group at all time intervals. At the same time, the NADH-cytochrome b5 methemoglobin reductase activity and the molybdenum content in erythrocytes of the bleeding group were significantly increased. Regressional analysis showed that there was a significantly positive correlation between the enzyme activity and the molybdenum content. It is proposed that molybdenum might be required for the enzyme activity

关 键 词：ACTIVITY NADH Effect of Repetitive Bleeding on NADH-Cytochrome b5 Methemoglobin Reductase Activity and Molybdenum Content in Erythrocytes of Rats 

分 类 号：Q592.1[生物学—生物化学] R559[医药卫生—血液循环系统疾病]