结节性硬化患儿脑电图及其与临床的关系  

EEG and its relation with clinical signs in children with tuberous sclerosis

作　　者：张志芳[1] 许燮萍[1] 贾莉娟[1] 周敏杰[1] 卢娜[1] 周玲[1] 

机构地区：[1]上海第二医科大学附属新华医院脑电图室,上海200092

出　　处：《临床神经电生理学杂志》2004年第1期25-27,共3页Journal of Clinical Electroneurophysiology

摘　　要：目的 :观察结节性硬化患儿的EEG特征及其与临床的关系。方法 :对 36例结节性硬化患儿的临床资料及EEG进行回顾性分析。结果 :36例结节性硬化患儿脑电图异常 2 6例 ,异常率为72 2 % ,2 4例有样放电 ,15例为局限性异常。EEG正常者其临床癫发作控制较好 ,多数智能发育正常。EEG局限性变化与临床神经定位体征之间关系密切 ,而与头颅CT局限性变化无明显关系。结论 :结节性硬化患儿中 ,EEG样放电常见 ,EEG异常多为局限性变化 ,并与临床神经定位体征有关 。Objective:To observe the EEG characteristics and the relationship with the clinical signs in children with tuberous sclerosis. Methods: The clinical data and EEG of 36 children with tuberous sclerosis were analyzed retrospectively. Results:EEG was found abnormal in 26 children out of 36 ones, at a abnormal rate of 72.2%. Twenty four of them displayed epileptiform discharges. local EEG changes were noted in 15 out of 26 children with abnormal EEG.The clinical seizures were controlled well in those with normal EEG and most of them had a well developed intelligence, Local EEG changes were closely related with the clinical localized signs but not with the local changes on cranial CT.Conclusions: Epileptiform discharges might be common in children with tuberous sclevosis EEG mainly display local changes, and it might be closely related with the clinical localized signs bnt not with the local changes on cranial CT.

关 键 词：结节性硬化 脑电图 痫样放电 儿童 临床意义 先天性疾病 

分 类 号：R741[医药卫生—神经病学与精神病学] R741.044[医药卫生—临床医学]