记忆商与丘脑血肿位置及体积的多元线性回归分析  

Correlation of memory quotients with site and size of thalamic hematoma:a multiple linear regression analysis

作　　者：毛永军[1] 

机构地区：[1]内蒙古医学院第一附属医院神经内科,内蒙古自治区呼和浩特市010050

出　　处：《中国临床康复》2004年第4期626-628,共3页Chinese Journal of Clinical Rehabilitation

摘　　要：目的:研究丘脑出血患者血肿中心位置,血肿体积与记忆商数的数量依存关系。方法:CT证实的丘脑出血患者31例,以大脑正中裂作一条直线为纵坐标,以颅骨的前后外缘的连线上前2/3作处作1条垂直线为横坐标。测定丘脑血肿中心在横坐标及纵坐标上的位置,分别用X,Y表示。血肿的体积用V表示。采用《临床记忆量表》进行记忆商数的测定。以记忆商数作为应变量,以X,Y及V为自变量,进行多元线性回归分析及相关分析。结果:记忆商数对于丘脑血肿中心位置X,Y及血肿体积V的多元线性回归方程:MQ=58.429-0.08227V+1.185X-1.083Y。方差分析结果表明自变量(X,Y,V)至少有一个与应变量(MQ)之间存在线性回归关系(P<0.01)。复相关系数(MultipleR)=0.852。个偏回归系数的t检验表明X与记忆商数,Y与记忆商数之间均存在线性回归关系(P<0.01),而V与记忆商数之间则无显著的线性关系(P>0.05)。结论:血肿中心位于丘脑的内侧,记忆障碍越重。同时,当血肿中心位于丘脑的前方时,记忆障碍亦更加明显。这可能与介导记忆有关的一些丘脑结构主要位于丘脑的前部和丘脑内侧部有关。丘脑血肿大小与记忆障碍程度无直接关系。AIM:To study the quantity-depended relationship of the memory quotients(MQ) to the central site and size of thalamic hematoma in patients with thalamic hem orrhage. METHODS:Totally 31 cases of thalamic hemorrhage diagnosed on the basis of cer ebral CT were enrolled in the study.A straight line longitudinally through the c erebrum was served as the ordinate,and the other perpendicular line as abscissas made through the line connecting the anterior-posterior borders of canium loc ated in the two-third point far from the anterior border. The ordinate and abs cissas were represented respectively as X and Y(independent variables),while V a s independent variable stood for the size of hematoma.Clinical memory scale was performed to determine MQ used as dependent variable.Multiple linear regression analysis and correlation analysis were performed. RESULTS:The multiple linear regression equation from the dependent variable(M Q) and the independent variables(V,X,Y) were formulated as:MQ=58.429-0.082 27V + 1.185X-1.083Y The analysis of variance showed that the linear regression correlation existe d between the dependent variable(MQ) and at lease one of the independent variabl es(X,Y,V)(P< 0.01).Multiple correlation coefficient(R) was 0.852.In the partial regression analysis coefficient, t test indicated that the linear regression cor relation existed between X and MQ,and between Y and MQ(P< 0.05),but not between V and the MQ(P > 0.05 ) . CONCLUSION:The memory disorder is more serious while the haematoma center is located at the medial part of the thalamus as well as located at the anterior pa rt of the thalamus.A possible reason is that most of the structures mediating me mory function are located at the medial part and the anterior part of the thalam us.There is no direct relationship between the size of the hamatoma and the seve rity of the memory disorder.

关 键 词：记忆商 丘脑血肿 丘脑体积 多元线性回归分析 诊断 记忆障碍 

分 类 号：R741[医药卫生—神经病学与精神病学]