缺血性脑血管病患者颈动脉粥样硬化与血脂、脉压的相关性研究  

Correlation study of carotid arteriosclerosis with plasma lipoprotein and pulse pressure in patients with ischemic stroke

作　　者：赵振宇[1] 赵志荣[1] 张玉珍[1] 公伟宏[1] 

机构地区：[1]山东临沂市沂水中心医院神经科,临沂276400

出　　处：《河南实用神经疾病杂志》2004年第2期20-22,共3页Henan Journal of Practical Nervous Diseases

摘　　要：目的　探讨缺血性脑血管病患者颈动脉粥样硬化与血液中脂类成分及脉压的关系。方法　用彩色多普勒超声观察及测量颈动脉内膜 中膜厚度、斑块情况 ,同时抽血检查血脂及载脂蛋白、测定脉压 ,并与性别、年龄相匹配的 13 0例健康人对照。结果　颈动脉粥样硬化者血脂及载脂蛋白除载脂蛋白A1 、HDL C降低外 ,其它均正常 ,颈动脉粥样硬化与载蛋白A1 呈强负相关 ;随着脉压的增加 ,IMT也逐渐增厚 ,各组间比较差异有显著性意义 (P <0 0 0 1)。结论　颈动脉粥样硬化与载脂蛋白A1 、HDLObjective To assess the correlation of carotid arteriosclerosis with plasma lipoprotein and pulse pressure in patients with ischemic stroke.Methods Carotid intima-media thickness and carotid vascular plaque were detected by ultrasonography,and plasma lipoprotein、apolipoprotein and pulse pressure were tested and contrasted with 130 healthy subjects matching in sex and age.Results Plasma lipoprotein and apolipoprotein were normal except that apolipoprotein A1 was reducted.Carotid arteriosclerosis was inversedy corrleated with apolipoprotein A1.Conclusion There is internal relation between carotid arteriosclerosis and apolipoprotein A1、HDL-C and pulse pressure.

关 键 词：缺血性脑血管病 颈动脉粥样硬化 血脂 脉压 相关性 超声检查 

分 类 号：R743.31[医药卫生—神经病学与精神病学] R543.4[医药卫生—临床医学]