双氯芬酸钠联合吗啡控释片治疗转移性骨肿瘤疼痛  

Morphine controlled-release tablets plus diclofenac sodium in the treatment of pain of bone metastatic carcinoma

作　　者：顾悦超[1] 张勇[1] 

机构地区：[1]复旦大学附属肿瘤医院麻醉科,上海200032

出　　处：《中国癌症杂志》2004年第1期78-79,共2页China Oncology

摘　　要：目的 :研究吗啡控释片联合双氯芬酸钠对于转移性骨肿瘤疼痛的镇痛效果及副作用。方法 :69例转移性骨肿瘤疼痛患者随机分为两组 ,Ⅰ组单用吗啡控释片 (3 0mg ,q 12h) ,Ⅱ组吗啡控释片 (3 0mg ,q 12h)联合应用双氯芬酸钠 (10 0mg ,q 12h)。观察两组的镇痛效果及副作用。结果 :Ⅱ组的镇痛效果优于I组 (P <0 .0 5) ,且两组副作用无明显差异。结论 :吗啡控释片和双氯芬酸钠联合应用能更好地控制转移性骨肿瘤疼痛 。Purpose:To study the efficacy and the side ef fe ct of morphine controlled-release tablets plus diclofenac sodium in the treatme nt of pain of metastatic bone carcinoma. Methods:69 patients with pain were randomly divided into two gr oups. Group Ⅰ was treated only with morphine controlled-release tablets (30 mg ,q 12 h),GroupⅡ with morphine controlled-release tablets (30 mg,q 12 h) and diclofenac sodium (100 mg,q 12 h). The analgesia effect and adverse reaction were observed. Results: Both have analgesia effect,but group Ⅱ was superior (P <0.05); and side effects were not significantly different between the two guoups .Conclusions:Morphine controlled-release tablets plus diclofen ac sodium can treat the pain of metastatic bone carcinoma more efficiently.

关 键 词：吗啡 双氯芬酸钠 转移性骨肿瘤 疼痛 

分 类 号：R730.6[医药卫生—肿瘤]