Expression changes in tau and microtubule-associated proteins in rat testicular interstitium  

作　　者：Zi-LongLiu Wan-HongZhang Sheng-HongLiu Xiao-LiWang FangWang Xue-JunKang 

机构地区：[1]FamilyPlanningInstitute,TongjiMedicalCollege,HuazhongScienceandTechnologyUniversity,Wuhan430030,China [2]DepartmentofAnatomy,TongjiMedicalCollege,HuazhongScienceandTechnologyUniversity,Wuhan430030,China

出　　处：《Asian Journal of Andrology》2004年第1期52-52,共1页亚洲男性学杂志（英文版）

摘　　要：Objective: To examine the expression of the tau protein and mi-crotubule-associated proteins (MAP) in the testicular interstitium of aged and young rats. Methods: Sprague-Dawley male rats were divided into a young group (6 months) and an aged group (28 months) of 10 animals each. The two-step immunohistochemistry method with the antibody against tau protein and MAPa was performed with the testis tissues. Results: The immunoreactive cells of the testicular interstilial tau protein were significantly increased (P<0.01) and those of the MAP significantly decreased (P<0.01) in the aged than in the young rats. Conclusion: The changes in the expression of the tau protein and MAP may be related to the aging process of the testis.

关 键 词：tau protein microtubule-associated proteins testis interstitium AGING IMMUNOHISTOCHEMISTRY 

分 类 号：R339.21[医药卫生—人体生理学]