高聚生配合放射治疗颈部淋巴结转移癌  

Curative Effect of Highly Agglutinative Staphylouoccin Plus Radiotherapy in Treatment of the Cervical Lymph Node Metastatic Carcinoma

作　　者：王冬果[1] 刘建军[1] 秦晓莉[1] 李翠珍[1] 安运轩 

机构地区：[1]河南省安阳市肿瘤医院放疗科,安阳市455000

出　　处：《医药论坛杂志》2004年第1期17-18,共2页Journal of Medical Forum

摘　　要：目的　采用高聚生瘤体内注射配合放射治疗颈部淋巴结转移癌 ,观察其疗效、不良反应并与单纯放射治疗进行比较。 方法　6 0例患者采用高聚生瘤体内注射配合放射治疗为综合组 ,同期单纯接受放射治疗 6 0例患者作为对照组。 1 2 0例患者均接受60 Co体外照射 ,照射剂量DT6 5 70GY/ 6 5 7周完成疗程。综合组采用高聚生瘤体内注射 ,2次 /周、6 1 2次为 1个疗程。 结果　瘤体完全消退率 ,综合组为 88 33% (5 3/ 6 0 ) ,对照组为 70 % (4 2 / 6 0 ) ,两组比较有差异 (P <0 0 5 )。 结论　高聚生瘤体内注射 ,使瘤体内药物浓度增高 ,配合放射治疗、增强了对肿瘤细胞的杀伤作用 。Objective To evaluate the curative effect of HASL plus radiotherapy in treatment of cervical lymph node metastatic carcinoma,and compare with radiotherapy Methods 120 patients were radomized into two groups:A and B group(60cases each).Both of them received radiotherapy 60 Co, 65~70GY,6 5~7 0 week.Moreover, A group was injected HASL into the metastatic lymph node,500~1500u biweekly,sum to 6~12times.Results CR of the metastatic lymph node was:A group 80 33%(53/60);B group 70%(42/60).There's obvious difference(P<0.05) Conclusion HASL combined with radiotherapy on cervical lymph node metastatic carcinoma is advantaged in clinical practice.

关 键 词：高聚生 放射治疗 颈部淋巴结转移癌 不良反应 瘤体注射 

分 类 号：R739.91[医药卫生—肿瘤] R733.4[医药卫生—临床医学]