恶性组织细胞病的早期诊断  

Early diagnosis of malignant histiocytosis

作　　者：柳金[1] 吴登蜀[2] 齐振华[2] 

机构地区：[1]北京大学深圳临床学院,广东深圳518036 [2]中南大学附属湘雅医院,长沙410008

出　　处：《临床误诊误治》2004年第3期159-160,共2页Clinical Misdiagnosis & Mistherapy

摘　　要：目的对恶性组织细胞病 (MH )的临床症状、病理特征进行分析 ,以提高早期诊断率。方法对本院收治的 16例、文献报道的 184例进行回顾性分析 ,总结出影响早期诊断的相关因素。结果MH早期临床表现为多系统受累 ,有发热 ( 96% )、肝大( 80 % )、脾大 ( 72 .5 % )、淋巴结肿大 ( 5 2 % )等 ,病理上主要为异型组织细胞增生。结论本组病例提示 ,根据病史和实验室检查 。Objective Clinical symptoms and pathological features of malignant histiocytosis (MH) were analyzed to obtain early diagnosis in clinical practice.Methods A retrospective analysis was performed on 16 hospitalized cases of MH and 184 reported cases on literature.Results At early stage of MH, it was manifested by multi-system involvement, fever(96%), hepatomegaly, splenomegaly and lymphadenectasis. Pahtologically, it showed heteromorphic histiocyte hyperplasis.Conclusions The findings of this study suggested that history and laboratory tests, especially multi-site bone marrow puncture should be able to improve the rate of early diagnosis.

关 键 词：恶性组织细胞病 早期诊断 骨髓穿刺 病理特征 异型组织细胞增生 碱性磷酸酶 

分 类 号：R733.1[医药卫生—肿瘤]