皮质下动脉硬化性白质脑病与多发梗塞性痴呆  

Subcortical arteriosclerotic encephalopathy and multi-infarct dementia

作　　者：高敬龙[1] 俞世勋[1] 孙玉珍[1] 

机构地区：[1]陕西省人民医院陕西省老年病研究中心

出　　处：《中风与神经疾病杂志》1992年第4期196-198,共3页Journal of Apoplexy and Nervous Diseases

摘　　要：通过48例皮质下动脉硬化性白质脑病(SAE)的CT特征和痴呆程度的对照分析。对本病和多发性脑梗塞性痴呆(MID)的关系进行探讨。认为SAE为多发性脑梗塞的病理类型之一,阐明了SAE和MID为两个相互交叉概念的新观点;讨论了SAE性痴呆与大脑损害部位和损害程度的关系以及相关危险因素;认为SAE性痴呆的病理生理基础有别于阿尔采莫氏病型痴呆(SDAT)。不是大脑皮质的严重萎缩,而是侧脑室周围及半卵圆中心等白质损害。其损害的范围和程度与痴呆的程度成正相关。The paper explores the correlation between SAE and dementia degree of 48 patients with SAE, and explores the relative dangerous factors and the correlation between SAED and the part, degree of the brain impairment. It was suggested that SAE was one of the pathologic types of MID and the pathologic base was the impairment of the white matter of the centrum semiovale and around the ventricle etc, was not a serious atrophy of the brain cortex. It was different from the senile dementia of Alzheimer type. There was a positive corrlation between the degree and the range of the white matter impairment and the degree of the dementia.

关 键 词：白质脑病 痴呆 脑萎缩 老年人 

分 类 号：R749.13[医药卫生—神经病学与精神病学]