MTT法检测肾脏肿瘤药物敏感性的分析  

Analysis of chemosensitivity of renal cell carcinoma by MTT assay

作　　者：陈海云[1] 张毅[2] 胡洁[2] 沈炜明[2] 

机构地区：[1]上海市普陀区中心医院药剂科,上海200062 [2]上海市第六人民医院药剂科,上海200233

出　　处：《药学服务与研究》2004年第1期67-68,共2页Pharmaceutical Care and Research

摘　　要：目的:分析肾脏肿瘤化疗药物的体外敏感性。方法:对19例肾脏肿瘤手术切除标本进行常规MTT药敏试验,检测临床常用的16种化疔药物的体外抑制率,并对检测结果进行分析。结杲:肾脏肿瘤对化疗药物的敏感性不高,而且不同个体对同一药物及不同药物对同一个体的敏感性差异较大。结论:单一药物的化疗不是肾脏肿瘤治疗的理想方案。Objective: To study the chemosensitivity of renal cell carcinoma. Methods: The chemosensitivity of 19 specimens of renal cell carcinoma to 16 chemotherapeutic drugs was studied with MTT method. Results: Renal cell carcinoma was insensitive to chemotherapeutic drugs, and the sensitivity varied with not only the drugs but also the individuals. Conclusion: Chemotherapy with single drug is not a good treatment for renal cell carcinoma.

关 键 词：肾脏肿瘤 MTT法 化疗药物 敏感性 药物治疗 药敏试验 

分 类 号：R737.11[医药卫生—肿瘤] R979.1[医药卫生—临床医学]