诱发大白鼠肝癌不同阶段病变与声象图比较研究  

Comparative Study of Pathologic.Change with Ultrasonogram of Artificially Induced Hepatic Carcinoma in White Rat

作　　者：张青萍[1] 余慧贞[1] 徐金锋[1] 朱明华[1] 柳建华[1] 汪元芳[1] 

机构地区：[1]同济医科大学附属同济医院超声诊断室

出　　处：《中国超声医学杂志》1992年第5期340-343,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：本文报道了采用二甲氨基偶氮苯(DAB)诱发大鼠肝癌模型,动态观察肝癌发生不同阶段的病理变化与超声图象的关系,结果显示,从诱癌发生的早、中、晚期其病变不同,声象图亦有相应的表现。并可发现0.3×0.4cm小癌结节,从肝癌形态发生学看,小肝细胞结节状增生,形成肝内多个细小低回声、等回声小结节,多为癌前期变化,系一值得注意的征象。最后。This paper reports the hepatic carcinoma (HC) model induced by Dimethylamioaco-henzene (DAB) in white rat. The relation between pathological changes of hepatic carcinoma and the ultrasonographic findings during different period were dynamically observed and compared. The results showed: in the early middle and later period of the tumor growth, the pathological features of HC were different corresponding with the different ultrasonographic appearances. A tiny cancer even 0.3×0.4cm had been found, so, small hypoechoic or isoechoic nodule as if a benign hepatocellular nodular hyperplasia might he a precancerous lesion. The clinical value of ultrasonographic observation of experimental hepatic carcinoma was finally discussed.

关 键 词：声象图 肝肿瘤 病变 超声检查 

分 类 号：R735.704[医药卫生—肿瘤]