便秘型肠易激综合征肛门直肠动力学的临床研究  

A clinical study on anorectal manometry in constipation-predominant irritable bowel syndrome

作　　者：孟欣颖[1] 朱有玲[2] 王学勤[2] 罗金燕[2] 张慧[1] 徐昌青[1] 李士玉[1] 

机构地区：[1]山东省千佛山医院消化内科,济南250014 [2]西安交通大学第二医院消化病研究室

出　　处：《胃肠病学和肝病学杂志》2004年第2期170-171,共2页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的　观察便秘型肠易激综合征 (IBS)的肛门直肠动力学改变。方法　采用灌注式测压装置测定 18例便秘型IBS患者和 15例健康人的肛门直肠压力、直肠对容量刺激的最低敏感量、最大耐受量及直肠顺应性。结果　便秘型IBS的直肠、肛门内外括约肌静息压力、内括约肌主动收缩压、模拟排便时直肠收缩压、内外括约肌净减压与对照组相比无显著性差异。肛门 直肠屏障压便秘型IBS组高于对照组 (P <0 0 5 )。直肠对容量刺激的最低敏感量便秘型IBS组低于对照组 (P <0 0 5 ) ,最大耐受量及顺应性均高于对照组 (P <0 0 1)。结论　便秘型IBS存在肛门直肠动力学异常 。Objective To study the anorectal motility in constipation-predominant irritable bowel syndrome (IBS-C).Methods Rectal visceral perception thresholds,rectal compliance and anorectal manometry were examined in the patients with constipation-predominant irritable bowel syndrome and the controls.Results The anorectal resting pressure,relaxation pressure had no significant difference between two groups.Anorectal barrier pressure was higher than normal (82.61±15.22,67.20±22.50,respectively).The lowest threshold of rectum in IBS-C was lower than controls (P<0.05),while the maximum tolerance of the rectum and rectal compliance were much higher than the controls (P<0.01).Conclusion There were anorectal motility abnormalities in constipation-predominant irritable bowel syndrome,which might contributes to the symptom of constipation.

关 键 词：便秘型肠易激综合征 肛门直肠 动力学 临床研究 

分 类 号：R574.4[医药卫生—消化系统]