脑囊虫病患者脑脊液氨基酸含量的变化  

CHANGES OF AMINO ACID LEVELS IN CEREBROSPINAL FLUID OF PATIENTS WITH NEUROCYSTICERCOSIS

作　　者：吴伟[1] 王述姮[1] 程道新[1] 张健[2] 

机构地区：[1]北京大学医学部基础医学院寄生虫学教研室,北京100083 [2]中国人民解放军第262医院神经内科

出　　处：《中国血吸虫病防治杂志》2004年第2期137-139,共3页Chinese Journal of Schistosomiasis Control

摘　　要：目的　观察脑囊虫病患者脑脊液氨基酸含量的变化。方法　采用全自动氨基酸分析仪检测 30例脑囊虫病患者和 13名对照组受检者脑脊液中氨基酸含量。结果　脑囊虫病患者脑脊液中苏氨酸、酪氨酸及苯丙氨酸含量与对照组差异有非常显著性 (P<0 .0 1) ;丝氨酸、谷氨酸、半胱氨酸、亮氨酸含量与对照组差异有显著性 (P<0 .0 5 )。结论　脑囊虫病患者脑脊液氨基酸含量发生改变 ,这可能与虫体的生长。Objective To observe the change of amino acid levels in the cerebrospinal fluid (CSF) of patients with neurocysticercosis. Methods The amino acid levels in CSF were measured in 30 cases of neurocysticercosis and 13 healthy persons as control group by Hitach 835-50 Automatic Amino Acid Analyzer. Results There were highly significant differences between patients with neurocysticercosis and the control group in the levels of threonine, tyrosine and phenylalanine (P<0.01); and significant differences in the levels of serine, glutamate, cysteine, leucine (P<0 05). Conclusion The change of amino acid levels in CSF of patients with neurocysticercosis might be related to the development of cysticercus and pathological changes in the brain.

关 键 词：脑囊虫病 脑脊液 氨基酸 

分 类 号：R532.33[医药卫生—内科学]