功能性消化不良患者胃液体排空和胃适应性舒张功能异常  

Abnormality of Gastric Liquid Emptying and Accommodation in Patients with Functional Dyspepsia

作　　者：李启祥[1] 朱良如[2] 侯晓华[2] 

机构地区：[1]江门市中心医院消化内科,广东江门529071 [2]华中科技大学同济医学院协和医院消化内科,湖北武汉430030

出　　处：《湖北民族学院学报（医学版）》2004年第1期1-4,共4页Journal of Hubei Minzu University(Medical Edition)

基　　金：国家自然科学基金项目 (3984 0 0 1 5 )

摘　　要：目的　检测功能性消化不良 (FD)患者的胃液体排空和近端胃适应性舒张功能 ,了解二者之间可能的关系。方法　采用超声法测定 1 5例健康自愿者和 30例FD患者饮水 5 0 0ml后的胃体—底前后内径变化 ,以了解胃液体排空情况 ,用电子恒压器恒压梯度扩张法测定近端胃的最大舒张容积 ,以了解其适应性舒张功能。结果　FD患者胃液体半排空时间明显延迟 (31 .1± 8.9minvs 2 3.7± 4 .6min ,P <0 .0 1 ) ,FD患者近端胃最大舒张容积较正常人显著小 (95 4 .3± 1 4 0 .8mlvs 1 0 6 2 .6± 1 2 2 .9ml,P <0 .0 5 ) ,4 6 .7% (1 4 / 30例 )的FD患者存在近端胃适应性舒张功能障碍。近端胃最大舒张容积与胃液体半排空时间的相关性分析表明 :近端胃适应性舒张容积越小 ,胃液体半排空时间延迟越明显 (r=- 0 .35 1 ,P <0 .0 5 )。结论　FD患者不仅存在胃液体排空延迟 ,而且还存在近端胃适应性舒张功能障碍 。Objective To investigate the relationship between gastric liquid emptying and gastric accommodation in patients with functional dyspepsia(FD). Methods Gastric accommodation was applied by barostat in 30 FD patients and 15 healthy controls. Gastric liquid emptying was measured by ultrasonography. Results The volume of gastric accommodation in FD patients was clearly lower than that in healthy controls(954.3±140.8 ml vs 1062.6±122.9 ml,P<0 05). 6.7%(14/30) FD patients had impaired gastric accommodation.The average time of 50% gastric liquid emptying was longer than that in healthy controls(31.1±8.9 min vs 23.7±4 6 min,P<0.01). The relevance analysis of the volume of gastric accommodation and the average time of 50% gastric liquid emptying showed that the lower the volume of gastric accommodation, the longer the delay of gastric liquid emptying(r=-0.351,P<0.05).Conclusions The patients with FD have not only impaired gastric accommodation, but also delayed gastric liquid emptying. They are related with each other.

关 键 词：功能性消化不良 胃液体排空 胃适应性舒张功能异常 超声法 

分 类 号：R573[医药卫生—消化系统]