高血压脑出血血肿冲洗液去甲肾上腺素动态变化的研究  

Dynamic changes of noradrenaline in hematomal fluid of hypertensive cerebral hemorrhage

作　　者：向强[1] 苏东[2] 文亮[1] 李昆[3] 

机构地区：[1]第三军医大学西南医院ICU,重庆00038 [2]第三军医大学西南医院麻醉科,重庆00038 [3]第三军医大学西南医院肝胆中心实验室,重庆00038

出　　处：《中国综合临床》2004年第5期438-439,共2页Clinical Medicine of China

摘　　要：目的　动态观察高血压脑出血血肿冲洗液去甲肾上腺素 (NE)的变化及其意义。方法　行微创颅内血肿清除术的中、重度 (出血量 >30ml)高血压脑出血患者 6 0例 ,连续监测血肿冲洗液中NE的动态变化。结果　高血压脑出血发病 6小时血肿冲洗液中即已检测出NE ,并于 4 8～ 72小时达高峰值 ,此后逐渐降低。结论　高血压脑出血后出血灶及周边脑组织去甲肾上腺素含量增加 ,并参与其后的病理过程 。Objective To investigate the dynamic changes of noradrenaline(NE) in hematomal fluid after hypertensive cerebral hemorrhage and its clinical significance.Methods 60 patients who accepted micro injury clearance of intracerebral hematoma were studied,whose changes of NE in hematomal fluid were monitored continuously.Results NE was detected in hematomal fluid 6h after hemorrhage,which reached peak at 48 72 h and then decreased gradually.Conclusion The focal of hypertensive cerebral hemorrhage and NE in the cerebral tissue are involved in the pathological process following cerebral hemorrhage whose level changes might be related with the prognosis of hypertensive cerebral hemorrhage.

关 键 词：脑出血 去甲肾上腺素 微创术 

分 类 号：R743.34[医药卫生—神经病学与精神病学]