某大学丢源事故受照人员染色体畸变分析及生物剂量估算  

Biological Dose Assessment by Analysis of Chromosome Aberration in Victims Exposed to a Lost Source at an University

作　　者：段志凯[1] 徐洪兰[1] 张淑贤[1] 王海燕[1] 李凤英[1] 

机构地区：[1]中国辐射防护研究院,太原030006

出　　处：《辐射防护通讯》2004年第2期18-20,共3页Radiation Protection Bulletin

摘　　要：应用常规染色体畸变分析技术 ,利用本实验室建立的离体照射人外周血染色体畸变的剂量效应曲线 ,对某大学钴源丢失事故中主要受照人员进行了染色体畸变分析和生物剂量估算。根据“双着丝点 +着丝粒环”频率估算的受照人员生物剂量范围为 0 .1 4～ 1 .0 9Gy。本次事故中 。Analysis of chromosome aberration(CA)for the main victims accidentally exposed to 60 Co γ ray at an university was conducted by means of routine CA analysis.Their biological doses were assessed by applying the dose response curve for human peripheral blood lymphocytes in vitro established at our laboratory. Based on the frequency of “dicentric + ring”,the whole body doses to four victims were estimated, ranging from 0.14 to 1.09 Gy. The apparent genetic damages were observed in bodies of the main victims in this accident.

关 键 词：丢源事故 受照人员 染色体畸变 生物剂量估算 大学 钴 遗传损伤 

分 类 号：R14[医药卫生—公共卫生与预防医学]