19例原发性胆囊癌疗效分析  

Analysis of Curative Effect in 19 Cases of Primary Carcinoma of Gallbladder

作　　者：程兴望[1] 吴玉叶 张召志 方先业[1] 

机构地区：[1]蚌埠医学院附属医院外科,安徽省蚌埠市233004 [2]安徽省淮北张矿分院病理科

出　　处：《中国肿瘤临床》2004年第2期104-105,共2页Chinese Journal of Clinical Oncology

摘　　要：目的:探讨浸润肌层的胆囊癌是否是局部疾病,行单纯胆囊切除术后是否要行二次根治手术治疗。方法:回顾分析了19例浸润肌层的原发性胆囊癌患者,8例行单纯胆囊切除术,11例行根治性淋巴结清扫术。68个区域淋巴结被检查。平均随访时间97个月。结果:组织学检查均未发现血管浸润,1例有淋巴管浸润。淋巴结均未见转移。10年生存率为89%,单纯胆囊切除术与根治术结果相比,差别无统计学意义。2例行根治术的患者死于肿瘤复发。结论:多数浸润肌层的早期原发性胆囊癌仅是局部扩散,行单纯胆囊切除术后不需再行根治术。Objective: To explore whether gallbladder carcinoma invading the muscle layer is a local disease and whether radical second resection is performed after simple cholecystectomy. Methods: A retrospective analysis of 19 patients with gallbladder cancer invading the muscle layer ,8 of whom underwent simple cholecystectomy and 11 radical resection with regional lymph node dissection, was performed.A total of 68 regional lymph nodes was examined for metastasis.The median follow-up time was 97 months. Results: No patient had blood vessel invasion on histology.Lymphatic vessel invasion was seen in one patient. The metastases were absent in all lymph nodes examined. Overall 10-year survival was 89per cent. The outcome after simple cholecystectomy was comparable to that after radical resection. This difference did not have statistical significance. Two patients who underwent radical resection died from tumour relapse. Conclusion: Most early gallbladder carcinoma spread only locally. The patients need not perform radical second resection when the depth of invasion of gallbladder carcinoma is limited to the muscle layer after simple cholecystectomy.

关 键 词：胆囊癌 手术 治疗 生存率 

分 类 号：R735.8[医药卫生—肿瘤]