电磁场暴露与痴呆:基于人群的病例对照研究  

Relationship between electromagnetic field exposure and dementia: a population-based case-control study

作　　者：牛富生[1] 解恒革[1] 王鲁宁[1] 王振福[1] 王晓红[1] 齐增飞[1] 

机构地区：[1]解放军总医院南三科,北京市100853

出　　处：《中国临床康复》2004年第10期1806-1807,共2页Chinese Journal of Clinical Rehabilitation

基　　金：国家自然科学基金资助项目(30070275)~~

摘　　要：目的:通过人群调查探讨电磁场暴露与痴呆的关系。方法:按照随机整群抽样,抽取1491名60岁以上男性军队离退休干部为研究对象,进行了认知功能和电磁场暴露状况的调查,进一步计算各类痴呆的患病率,并通过Logistic回归统计电磁场暴露与痴呆和阿尔茨海默病(Alzheimer'sdisease,AD)患病危险性的比数比(OR)以及年龄和教育水平校正后的OR及其95%可信区间(CI)。结果:痴呆和AD的患病率分别为3.62%和1.74%。单因素分析发现电磁场暴露者患痴呆和AD的OR分别为1.2(95%CI1.042～3.526)和2.7～95%CI1.192～6.143)(P<0.05)。经文化水平校正后,患痴呆和AD的OR分别为2.1(95%CI1.102～3.764)和2.9(95%CI1.266～6.586),但经年龄校正后结果无统计学意义。经年龄组和文化水平共同校正后,患AD的OR为2.3(95%CI为1.003～5.496)。结论:电磁场暴露与痴呆的关系值得关注,其可能为痴呆的危险因素之一。AIM:To investigate the relationship between electromagnetic field(EMF) exposure and dementia based on the population survey. METHODS:A total of 1 491 male veterans,aged over 60 years,currently living in rest home, were included according to the randomized cluster sampling method.Questionnaires were carried out to investigate the condition of cognitive function and electromagnetic field exposure to calculate the prevalence rate of each dementia.Logistic regression analysis was performed to calculate the odd ratio(OR) of the prevalence rates of dementia to Alzheimer's disease(AD),OR and 95%confidence interval(CI) after the correction of age and education background. RESULTS:The prevalence rates of dementia and AD in the population aged 60 years or above were 3.62%and 1.74%,respectively.Those with an early occupational EMF exposure had a higher OR to develop dementia and Alzheimer's disease(1.2 with a 95%CI of 1.042-3.526 vs. 2.7 with 95%CI of 1.192-6.143,respectively,P< 0.05).The education adjusted OR was still significant(OR=2.1,95%CI,1.102 to 3.764 vs.OR=2.9, 95%CI,1.266 to 6.586,respectively),but the age adjusted OR was no longer significant.Those with an EMF exposure had an excess risk for developing AD,with an age education adjusted OR of 2.3(95%CI,1.003 to 5.496). CONCLUSION:The relationship between early occupational EMF exposure and dementia needs to be studied further,and early occupational exposure to EMF may be a risk factor for dementia.

关 键 词：电磁场暴露 调查 老年痴呆 阿尔茨海默病 危险因素 

分 类 号：R749.16[医药卫生—神经病学与精神病学]