善得定治疗肝硬化食管静脉曲张破裂出血  

Effects of sandostatin on esophageal variceal bleeding in cirrhotic patients

作　　者：莫梅[1] 

机构地区：[1]重庆市第三人民医院老年科,重庆400014

出　　处：《现代医药卫生》2004年第9期724-725,共2页Journal of Modern Medicine & Health

摘　　要：目的 :评价善得定治疗肝硬化食管静脉曲张破裂出血的疗效。方法 :将65例肝硬化食管静脉曲张破裂出血分为两组 ,善得定组用善得定100μg静注 ,继以25μg/小时持续静脉滴注72小时 ,垂体后叶素组用垂体后叶素10U静注后继以0.2U/分维持静滴72小时。结果 :治疗组总止血率为85.3 % ,对照组为41.9 % ,两组比较差异有高度显著性 (P<0.01),且治疗组不良反应显著降低。结论 :善得定能有效治疗肝硬化食管静脉曲张破裂出血 ,疗效优于垂体后叶素。Objective:To evaluate the effectiveness of sandostatin in the treatment of esophageal variceal bleeding in cirrhotic pa-tients.Methods:65of esophageal variceal bleeding in cirrhotic patients were divided into sandostatin group and vasopressin group.Sandostatin was administered100ug intravenously and then as a continuous infusion at a rate of25ug per hour for72hours.Vasopressin was given10units of piutitrin IV and then as a continuous infusion at a rate of0.2units per minute.Results:The hemostatic rate in sandostatin group and vasopressin group was85.3%and41.9%respectively.The hemostatic rate of sandostatin group was obviously higher than that of vasopressin group(P<0.01).Adverse effects in sandostatin group was sigficantly less than those in vasopressin group.Conclusion:Sandostatin can effectively control the esophageal variceal bleeding in cirrhotic patients.

关 键 词：善得定 治疗 肝硬化 食管静脉曲张破裂出血 

分 类 号：R575.2[医药卫生—消化系统]