离子型与非离子型MR对比剂对肝脏病变的增强效果比较  

Two Different Contrast Agents for MR of Gd-DTPA-BMA and Gd-DTPA of Multi-phase Dynamic Contrast Enhanced MR Scan of Hand-push Bolus for Hepatic Lesions

作　　者：王玮[1] 魏经国[1] 梁国民[1] 黄进[1] 徐家宽[1] 孙巧黎[1] 卞玉刚[1] 

机构地区：[1]第四军医大学唐都医院放射科,陕西西安710038

出　　处：《实用放射学杂志》2004年第1期38-41,共4页Journal of Practical Radiology

摘　　要：目的　对比离子型钆喷酸葡胺 (Gd -DTPA)和非离子型钆双胺MR对比剂 (Gd -DTPA -BMA)在肝脏病变手推团注多时相增强扫描中的增强效果。方法　 5 8例肝脏疾病患者 (男 3 1例 ,女 2 7例 ,年龄 3 0～ 77岁 )分 2组 ,第 1组 :3 0例 (男 16例 ,女 14例 ) ,采用Gd -DTPA -BMA。第 2组 :2 8例 (男 17例 ,女 11例 ) ,采用Gd -DTPA。行MR手推团注多时相增强扫描。结果　Gd -DTPA -BMA组 :增强效果满意者 2 3例 (77% ) ,增强效果一般者 6例 (2 0 % ) ,增强效果差者 1例 (3 % )。Gd -DTPA组 :增强效果满意者 2 2例(79% ) ,增强效果一般者 6例 (2 1% )。结论　在肝脏疾病MR手推团注多时相增强扫描中 ,Gd -DTPA -BMA和Gd -DTPA均可达到满意的增强效果 ,安全及有效性两者无显著性差异。Gd -DTPA -BMA粘滞度小 ,利于快速推注。Objective To evaluate the safety and effectiveness of Gd-DTPA and Gd-DTPA-BMA of multi-phase dynamic contrast enhanced MR scan of hand-push bolus for hepatic lesions. Methods 58 patients suffering from hepatic diseases (31 men, 27 women; mean age 53.5) were examined by multi-phase dynamic contrast enhanced MR scan. The first group: 30 cases (16 men, 14 women), intravenous injection Gd-DTPA-BMA was employed. The second group: 28 cases (17 men, 11 women), intravenous injection Gd-DTPA was employed. Results In the first group the enhancement was effective in 23 cases (77%), medium in 6 cases (20%), and inadequate in 1case (3%). In the second group, the enhancement was effective in 22 cases (79%), medium in 6 cases (21%).Conclusion The safety and effectiveness of Gd-DTPA-BMA and Gd-DTPA of Multi-phase dynamic contrast enhanced MR scan of hand-push bolus for liver are identical. The adhesive density of Gd-DTPA-BMA is weak, so it is advantageous to fast hand-push bolus.

关 键 词：离子型MR对比剂 非离子型MR对比剂 肝脏病变 Gd-DTPA-BMA 离子型钆喷酸葡胺 GD-DTPA 

分 类 号：R575[医药卫生—消化系统] R445.2[医药卫生—内科学]