胰腺癌细胞的增殖同膜脂质饱和度、膜胰岛素受体的关系  

Correlation of Proliferation of Pancreatic Cancer Cells With Both Saturation Index and Cell Membrane Insulin Receptors

作　　者：么崇正[1] 赵玉沛[1] 邱辉忠[1] 高维生[1] 

机构地区：[1]中国医学科学院协和医院

出　　处：《中国医学科学院学报》1992年第6期397-401,共5页Acta Academiae Medicinae Sinicae

摘　　要：外源性表皮生长因子(或生长抑素)能促进(或抑制)胰腺癌细胞的增殖。胰腺癌细胞增殖速率的高低与细胞膜脂质饱和度的降、升;与膜胰岛素受体数量的增减密切相关。测定细胞膜脂质饱和度和胰岛素受体数量,是判断胰腺癌增殖状态的灵敏指标,有一定临床价值。Exogenous epidermal growth, factor (or somatostatin) can stimulate (or inhibit) proliferation of pancreatic cancer cells, with a corresponding decrease (or increase) of the saturation index of the cell membrane and up-regulation (or down-regulation) of insulin receptor expression.By measuring the saturation index and insulin receptor numbers on the cell membrane it may be possible to evaluate the curative effects of treatment on pancreatic cancer at an early time.

关 键 词：生长抑期 膜脂质 胰岛素 胰腺肿瘤 

分 类 号：R735.902[医药卫生—肿瘤]