胰头癌切除术后复发因素的探讨  

Inquire into factors influencing recurrence following resection of carcinoma of the head of pancreas

作　　者：母德清[1] 彭淑牖[1] 王国凤[2] 

机构地区：[1]浙江大学医学院第二附属医院普外,杭州310009 [2]浙江大学医学院第二附属医院病理科,杭州310009

出　　处：《中华医学杂志》2003年第19期1657-1660,共4页National Medical Journal of China

摘　　要：目的　探讨影响胰头癌术后复发的因素 ,提高胰腺癌患者的生存率。方法　回顾性分析了 1995年 1月至 1998年 12月间住院的 5 6例胰头癌患者 ,35例接受胰头十二指肠切除术 ,同期 2 1例接受扩大根治术 ,列表分析术后复发的因素。所有生存的患者均随访 3年以上以明确胰头癌切除术后复发的因素。结果　患者术后 3年内死于复发。因复发累积死亡率胰十二指肠切除术组为5 1 4 % ;扩大根治术组为 4 2 9% ,两组间差异有显著意义。结论　肿瘤直径超过 4cm ,超过第二站的淋巴结转移和“间隙浸润”Objective Inquire into factors influencing recurrence following resection of carcinoma of the head of pancreas to raise survival rate of pancreatic cancer. Methods We performed a retrospective review of 56 pancreatic resections with carcinoma of the head of pancreas operated from January 1995 to December 1998. 35 patients tolerated the Whipple operadure in comparision with 21 patients received the extended radical operation contemporaneously.All patients were followed up more than 3 years to find out factors influencing recurrence following resection of carcinoma of the head of pancreas. Results Deaths within 3-years after operation were duo to recurrence, the cumulative rate of death from recurrence 51.4% in the Whipple procedure and 42.9% in the Extended radical operative procedure, significant difference in two groups. Conclusion Tumour size exceed 4 cm with severe retropancreatic invasion, lymph node involvement surpass the second group are at high risk for recurrence.

关 键 词：胰头癌 肿瘤切除术 术后复发 危险因素 肿瘤转移 预后 

分 类 号：R735.9[医药卫生—肿瘤]