疑难病研究——原发性骨结外淋巴瘤  

A difficult and complicated case study:primary extra nodal lymphoma of bone

作　　者：郑湘榕[1] 尹飞[1] 祁伯祥[1] 

机构地区：[1]中南大学湘雅医院儿科,湖南长沙410008

出　　处：《中国当代儿科杂志》2004年第2期125-127,共3页Chinese Journal of Contemporary Pediatrics

摘　　要：原发性骨结外淋巴瘤是指原发于骨骼部位的淋巴瘤 ,儿童罕见 ,其病因未明。临床表现以局部骨骼病变为主 ,骨关节疼痛和局部骨骼肿胀是最常见的症状 ,伴或不伴有全身症状。放射形态学检查为骨质溶解性病损。病理形态学上存在多样性 ,大部分为大B细胞来源淋巴瘤 (DLBCL)。该病确诊需经骨组织病理活检。治疗采取综合治疗 ,包括化疗与放疗 。Primary extra nodal lymphoma of bone means the malignant lymphoma presents initially in bones. It is a rare disease of unknown etiology in children. The disorder mainly manifests in localized bone lesions. Bone arthrodynia and localized bone swelling are the most common symptoms, with or without systemic symptoms. Radiologic examinations reveal osteolytic lesions. The histological features are various, and the majority of histology are diffuse large B cell lymphomas. Diagnosis of the disease may be confirmed by bone biopsy. The prognosis of the patients with this disorder is comparatively favorable after general treatment with chemotherapy and radiation therapy.

关 键 词：原发性骨结外淋巴瘤 综合治疗 病因 预后 鉴别诊断 

分 类 号：R738.1[医药卫生—肿瘤]