小儿急性白血病血清凝血酶原前体蛋白的临床研究  

The clinical study on serum precursor of prothrombin in children with acute leukemia

作　　者：张宝玺[1] 杨秋格[1] 张会丰[1] 

机构地区：[1]河北医科大学第二医院儿科,050000

出　　处：《中国小儿血液》2004年第2期67-68,共2页China Child Blood

摘　　要：目的 　探讨小儿急性白血病出血倾向与机体维生素K的关系。方法 　采用ELISA法检测血清凝血酶原前体蛋白水平 ,它是反映机体维生素K缺乏最敏感的指标。结果　 4 0例ALL和ANLL化疗前和化疗后及 2 0例正常儿童凝血酶原前体蛋白水平均小于最低检测限 ( 0 1 5AU/ml) ,结论　小儿白血病的出血与维生素K无明显关系。Objective To discuss the relation between tendency of bleeding and vitamin k of human body in children acute leukemia. Methords We adopted ELISA to measure the level of serum precursor of prothrombin, which is the most sensitive target of reflecting lack of vitamin k in human body. Results The level of serum precursor of prothrombin were lower than 0.015 AU/ml in 40 cases acute leukemia before and after treatment and normal children. Conclusion It is no relation between the bleeding and vitamin k in children acute leukemia.

关 键 词：小儿 急性白血病 血清凝血酶 原前体蛋白 临床分析 

分 类 号：R733.71[医药卫生—肿瘤]