浙江省温州地区7～16岁人群Tourette综合征患病率调查  

Study on the prevalence of Tourette syndrome in children and juveniles aged 7-16 years in Wenzhou area

作　　者：金嵘[1] 郑荣远[1] 黄文武 徐惠琴[1] 邵蓓[3] 陈宏[4] 邹有林 黄海波[1] 邹长林[1] 周祖木[6] 

机构地区：[1]浙江温州医学院附属第一医院流行病学教研室神经内科 [2]温州市精神病院 [3]浙江温州医学院附属第一医院流行病学教研室神经内科1325000 [4]浙江温州医学院附属第一医院精神科 [5]温州市鹿城区教委 [6]温州市疾病预防控制中心

出　　处：《中华流行病学杂志》2004年第2期131-133,共3页Chinese Journal of Epidemiology

基　　金：浙江省温州市科学技术委员会基金(S2000A16)

摘　　要：目的 研究温州地区7～16岁学生Tourette综合征的现状和分布特点。方法 采用分层整群抽样方法,对温州地区9742名7～16岁学生进行横断面流行病学调查。结果 Tourette综合征总患病率为0.43％,男生为0.74％,女生为0.07％,男生Tourette综合征的患病率显著高于女生(X^2=25.09,P<0.001,男女生患病率比为10.95,95％CI:3.38～35.46);各年龄组患病率以9～10岁组为最高;平均发病年龄(7.7±2.7)岁,发病高峰在6～7岁,占总病例数的45.2％;延迟诊断率78.6％(33/42),漏诊率42.9％(18/42),误诊率23.8％(10/42)。结论 Tourette综合征在温州地区学生中较多见,与年龄、性别有关,有较多的漏诊和误诊,应加强临床医生及社会人群对该病的认识。Objective To study the prevalence and distribution of Tourtte syndrome (TS). Methods Nine thousand, seven hundred and forty-two children and juveniles aged 7-16 years in Wenzhou were studied, using cluster random sampling method. Results The prevalence of TS among school-age children was estimatal to be 0. 43% (0. 74% for males and 0. 07% for females). The prevalence of male children and juveniles was higher than that of female children and juveniles (X^2 = 25. 09, P< 0. 001, prevalence ratio= 10. 95, prevalence ratio 95 % CI: 3. 38-- 35. 46). The highest prevalence of TS was between 9-10 years old. The mean age at onset of TS was 7. 7±2. 7 years, with 45. 2% of them among 6-7 year olds. The rate of delayed diagnosis and rates of misdiagnosis and misclassification of the syndromes were 78. 6%, 42. 9% and 23. 8%, respectively. Conclusion Tourette syndrome had been a common disease of children and juveniles in Wenzhou area. The disease was correlated with age and sex, often misdiagnosed and misclassified. Physicians and as well as general publics should be trained to identify the cases.

关 键 词：浙江 温州地区 7-16岁 人群 TOURETTE综合征 患病率 神经精神疾病 

分 类 号：R749.94[医药卫生—神经病学与精神病学]