Synthesis and Crystal Structure of 2(1-Phenyl-3-methyl-5-chloro-1H-pyrazol- 4-yl)-3-(1-naphthoylamido)-4-thiazolidinone  

作　　者：李明  文丽荣  景淑霞  赵桂龙  杨华铮  

机构地区：[1]Institute of Elemento-organic Chemistry,Nankai University,Tianjin 300071,China,College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qingdao 266042,China,State Key Laboratory of Applied Organic Chemistry,Lanzhou [2]College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qingdao 266042,China [3]Institute of Elemento-organic Chemistry,Nankai University,Tianjin 300071,China

出　　处：《Chinese Journal of Structural Chemistry》2004年第4期366-370,共5页结构化学（英文）

基　　金：theNSFofShandongProvince(Y2003B01),NNSFC(20172031);theFundfortheDoctoralProgramofHigherEducation.

摘　　要：The crystal structure of 2(1-phenyl-3-methyl-5-chloro-1H-pyrazol-4-yl)-3-(1- naphthoylamido)-4-thiazolidinone (C24H19ClN4O2S, Mr = 462.94) has been determined by single- crystal X-ray diffraction method. The crystal belongs to monoclinic, space group P21/c with a = 11.623(5), b = 11.579(5), c = 16.619(7) ? b = 90.112(8), V = 2237(2) 3, Z = 4, Dc = 1.375 g/cm3, m = 0.294 mm-1, F(000) = 960, R = 0.0492 and wR = 0.0768 for 3932 unique reflections with 1897 observed ones (I > 2s(I)). X-ray analysis reveals that there exist both intra-and intermolecular hydrogen bonds in the crystal lattice.The crystal structure of 2(1-phenyl-3-methyl-5-chloro-1H-pyrazol-4-yl)-3-(1- naphthoylamido)-4-thiazolidinone (C24H19ClN4O2S, Mr = 462.94) has been determined by single- crystal X-ray diffraction method. The crystal belongs to monoclinic, space group P21/c with a = 11.623(5), b = 11.579(5), c = 16.619(7) ? b = 90.112(8), V = 2237(2) 3, Z = 4, Dc = 1.375 g/cm3, m = 0.294 mm-1, F(000) = 960, R = 0.0492 and wR = 0.0768 for 3932 unique reflections with 1897 observed ones (I > 2s(I)). X-ray analysis reveals that there exist both intra-and intermolecular hydrogen bonds in the crystal lattice.

关 键 词：PYRAZOLE 4-THIAZOLIDINONE crystal structure synthesis 

分 类 号：O626.21[理学—有机化学]