4-THIAZOLIDINONE

作品数:11被引量:27H指数:2
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相关领域:理学化学工程更多>>
相关期刊:《Chinese Journal of Structural Chemistry》《Chemical Research in Chinese Universities》《International Journal of Organic Chemistry》《Chinese Chemical Letters》更多>>
相关基金:国家自然科学基金高等学校学科创新引智计划更多>>
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Synthesis of Novel 4-Thiazolidinone and Bis-Thiazalidin-4-One Derivatives Derived from 4-Amino-Antipyrine and Evaluated as Inhibition of Purine Metabolism Enzymes by Bacteria
《International Journal of Organic Chemistry》2019年第2期85-95,共11页Reda M. Abdel Rahman Abdulrahman S. Alharbi Nawaa A. Alshammari 
Novel 4-thiazolidione and 1,4-bis-thiazolidinone derivatives bearing antipyrine moiety have been obtained from condensation of 4-aminoantipyrine 1 with aromatic/heteroaldehydes followed by cycloaddition with mercaptoa...
关键词:Synthesis 4-Thiazolidinones ANTIPYRINE INHIBITION of Purine Metabolism ENZYMES BACTERIA 
Synthesis of Some New Thioethers and 4-Thiazolidinones Bearing 3-(Pyridine-4'-yl)-1,2,4-Triazino[5,6-<i>b</i>]Indole Moiety as Antifungal Agents
《International Journal of Organic Chemistry》2019年第1期37-46,共10页Wafa A. Baker Bawazir 
Some new asymmetric thioethers 5 and 4-thiazolidinones 6 have been obtained from condensation of 5-formyl-3-(pyridin-4'-yl)-1,2,4-triazino[5,6-b] indole (3) with halogenated aromatic amines followed by addition of thi...
关键词:THIOETHERS Thiazolidnones 1 2 4-Triazino INDOLE FUNGICIDAL Cycloaddition 
3D-QSAR and Docking Studies of 1,3,4-Thiazolidinone Derivatives Using R-Group Search and Surflex-dock被引量:19
《Chinese Journal of Structural Chemistry》2019年第3期464-475,共12页TONG Jian-Bo WANG Yang LEI Shan QIN Shang-Shang 
supported by the National Natural Science Foundation of China(21475081,21275094);the Graduate Innovation Fund of Shaanxi University of Science and Technology
In this paper, a three-dimensional quantitative structure-activity relationships(3 D-QSAR) study for 20 HIV-1 reverse transcriptase(RT) inhibitors was established using Topomer Co MFA. The models were built based on d...
关键词:QSAR RT INHIBITORS Topomer COMFA Topomer SEARCH design of new INHIBITORS molecular docking 
Synthesis and Antifungal Activity of Some New Fluorine-Substituted 4-Thiazolidinone Bearing 1,2,4-Triazinone
《International Journal of Organic Chemistry》2018年第1期170-175,共6页Layla A. Taib 
Fluorine substituted 4-thiazolidinone 5 bearing 1,2,4-triazinone obtained from the condensation of 3-Amino-6(2’-aminophenyl)-1,2,4-triazin-5(4H)-one (2) with an aromatic aldehyde followed by cycloaddition with mercap...
关键词:SYNTHESIS FLUORINE 4-THIAZOLIDINONE 1 2 4-Triazin FUNGAL 
A catalysis study of mesoporous MCM-41 supported Schiff base and CuSO_4·5H_2O in a highly regioselective synthesis of 4-thiazolidinone derivatives from cyclocondensation of mercaptoacetic acid被引量:2
《Chinese Chemical Letters》2016年第3期335-339,共5页Hai-Xia Pang Yong-Hai Hui Kui Fan Xue-Jian Xing Yang Wu Jing-Hui Yang Wei Shi Zheng-Feng Xie 
the National Natural Science Foundation of China(Nos.21162026,21262034 and 21362036);Doctoral Fund of Xinjiang University(No.BS110111)for financial support,Xinjiang University Analytical&Testing Center for instrumental analyses,and Adamas-beta Chemical Co.,for all chemical reagents
Mesoporous MCM-41 supported Schiff base and Cu SO4· 5H2 O shows high catalytic activity in the cyclocondensation of mercaptoacetic acid with imines(or aldehydes and amines) to afford pharmaceutically important thia...
关键词:MCM-41 Schiff base Cyclocondensation Mercaptoacetic acid Catalysis 
Design, Synthesis and Antitumor Activity of Novel Indolin-2-one Derivatives Containing 4-Thiazolidinone Moiety
《Chemical Research in Chinese Universities》2015年第2期235-243,共9页LIU Zijian HOU Yunlei ZHANG Guogang XU Ning MI Bin GONG Ping ZHAO Yanfang 
Supported by the Program for Innovative Research Team of the Ministry of Education of China and the Program for Liaoning Innovative Research Team in University, China(No.IRT1073), and the National Natural Science Foundation of China (No.81202405)
A series of novel indolin-2-one derivatives containing 4-thiazolidinone moiety(7a--7r) were synthesized and evaluated for their in vitro antitumour activities against MDA-MB-231 (human breast cancer), H460(human ...
关键词:lndolin-2-one 4-THIAZOLIDINONE Antitumour activity 
Design,synthesis and evaluation of PPAR gamma binding activity of 2-thioxo-4-thiazolidinone derivatives
《Chinese Chemical Letters》2015年第1期63-68,共6页Li Zhou Ye Zhong Meng-Zhu Xue Dong Kuang Xian-Wen Cao Zhen-Jiang Zhao Hong-Lin Li Yu-Fang Xu Rui Wang 
supported by the National Natural Science Foundation of China(Nos.81072627,81230090 and 81222046);Shanghai Committee of Science and Technology(Nos.12431900901 and 12401900801);the Fundamental Research Funds for the Central Universities(111 Project,No.B07023)
We designed and synthesized a series of 2-thioxo-4-thiazolidinone derivatives and evaluated them on peroxisome proliferator activated receptor γ(PPARγ) binding activities.Through the biological assays,compounds 18...
关键词:2-Thioxo-4-thiazolidinone Peroxisome proliferator activated receptorγ Binding activities SAR Molecular docking 
N-Methylpyridinium tosylate catalyzed green and efficient synthesis of some novel 2,4-disubstituted thiazoles and 4-thiazolidinones被引量:1
《Chinese Chemical Letters》2012年第11期1221-1224,共4页Deepika Gautam Poonam Gautam R.P.Chaudhary 
A convenient solvent less cyclocondensation from thiosemicarbazone of benzofuranone and chloroacetic acid using an ionic liquid, N-methylpyridinium tosylate for obtaining novel 4-thiazolidinones in excellent yields is...
关键词:4-Thiazolidinones THIAZOLES Grinding Ionic liquid CYCLOCONDENSATION THIOSEMICARBAZONES 
Synthesis and Crystal Structure of 2-(1-Naphthalenylamino)-4-thiazolidinone
《Chinese Journal of Structural Chemistry》2012年第7期977-980,共4页赵华绒 王昱丹 朱婷婷 刘曼琼 孟祥武 
supported by the Natural Science Foundation of Zhejiang Province (Y4080234)
The compound 2-(1-naphthalenylamino)-4-thiazolidinone was synthesized by the reaction of 1-(naphthalene-1-yl)thiourea with ethyl chloroacetate in an ionic liquid, and its structure was characterized by IR, 1H NMR ...
关键词:crystal structure ionic liquid 4-THIAZOLIDINONE X-ray diffraction thermal analysis 
Reaction of thiocarboxanilide derivatives of 2-phenylimino-3-phenyl-4-thiazolidinone and 1,3-diphenyl-2-thioxo-4-imidazolone with hydrazonoyl halides and active chloromethylene compounds被引量:1
《Natural Science》2011年第3期199-207,共9页Hamdi M. Hassaneen Omar A. Miqdad Nada M. Abunada Ahmad A. Fares 
The potassium salts of thiocarboxanilide of 2- phenylimino-3-phenyl-4-thiazolidinone and 1,3- diphenyl-2-thioxo-4-imidazolone react with hydrazonoyl halides in N,N-dimethylformamide to afford the corresponding 1,3,4-t...
关键词:Hydrazonoyl HALIDES 1 3 4-Thiadiazoline THIAZOLIDINONE 
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