相关期刊:《Chinese Journal of Structural Chemistry》《Chemical Research in Chinese Universities》《International Journal of Organic Chemistry》《Chinese Chemical Letters》更多>>
Novel 4-thiazolidione and 1,4-bis-thiazolidinone derivatives bearing antipyrine moiety have been obtained from condensation of 4-aminoantipyrine 1 with aromatic/heteroaldehydes followed by cycloaddition with mercaptoa...
Some new asymmetric thioethers 5 and 4-thiazolidinones 6 have been obtained from condensation of 5-formyl-3-(pyridin-4'-yl)-1,2,4-triazino[5,6-b] indole (3) with halogenated aromatic amines followed by addition of thi...
supported by the National Natural Science Foundation of China(21475081,21275094);the Graduate Innovation Fund of Shaanxi University of Science and Technology
In this paper, a three-dimensional quantitative structure-activity relationships(3 D-QSAR) study for 20 HIV-1 reverse transcriptase(RT) inhibitors was established using Topomer Co MFA. The models were built based on d...
Fluorine substituted 4-thiazolidinone 5 bearing 1,2,4-triazinone obtained from the condensation of 3-Amino-6(2’-aminophenyl)-1,2,4-triazin-5(4H)-one (2) with an aromatic aldehyde followed by cycloaddition with mercap...
the National Natural Science Foundation of China(Nos.21162026,21262034 and 21362036);Doctoral Fund of Xinjiang University(No.BS110111)for financial support,Xinjiang University Analytical&Testing Center for instrumental analyses,and Adamas-beta Chemical Co.,for all chemical reagents
Mesoporous MCM-41 supported Schiff base and Cu SO4· 5H2 O shows high catalytic activity in the cyclocondensation of mercaptoacetic acid with imines(or aldehydes and amines) to afford pharmaceutically important thia...
Supported by the Program for Innovative Research Team of the Ministry of Education of China and the Program for Liaoning Innovative Research Team in University, China(No.IRT1073), and the National Natural Science Foundation of China (No.81202405)
A series of novel indolin-2-one derivatives containing 4-thiazolidinone moiety(7a--7r) were synthesized and evaluated for their in vitro antitumour activities against MDA-MB-231 (human breast cancer), H460(human ...
supported by the National Natural Science Foundation of China(Nos.81072627,81230090 and 81222046);Shanghai Committee of Science and Technology(Nos.12431900901 and 12401900801);the Fundamental Research Funds for the Central Universities(111 Project,No.B07023)
We designed and synthesized a series of 2-thioxo-4-thiazolidinone derivatives and evaluated them on peroxisome proliferator activated receptor γ(PPARγ) binding activities.Through the biological assays,compounds 18...
A convenient solvent less cyclocondensation from thiosemicarbazone of benzofuranone and chloroacetic acid using an ionic liquid, N-methylpyridinium tosylate for obtaining novel 4-thiazolidinones in excellent yields is...
supported by the Natural Science Foundation of Zhejiang Province (Y4080234)
The compound 2-(1-naphthalenylamino)-4-thiazolidinone was synthesized by the reaction of 1-(naphthalene-1-yl)thiourea with ethyl chloroacetate in an ionic liquid, and its structure was characterized by IR, 1H NMR ...
The potassium salts of thiocarboxanilide of 2- phenylimino-3-phenyl-4-thiazolidinone and 1,3- diphenyl-2-thioxo-4-imidazolone react with hydrazonoyl halides in N,N-dimethylformamide to afford the corresponding 1,3,4-t...