THIAZOLIDINONE

作品数：4被引量：2H指数：1
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相关期刊：《Natural Science》《Chemical Research in Chinese Universities》《Journal of Biomedical Research》《International Journal of Organic Chemistry》更多>>
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A novel synthesized prodrug of gemcitabine based on oxygen-free radical sensitivity inhibited the growth of lung cancer cells
《The Journal of Biomedical Research》2023年第5期355-366,共12页Xinlu Chai Yuting Meng Wei Ge Juan Wang Fei Li Xue Jun Wang Xuerong Wang 
supported by the National Natural Science Foundation of China(Grant Nos.81972763 and 81473241).
In the present study,we introduced the H2O2-sensitive thiazolidinone moiety at the 4th amino group of gemcitabine(GEM)to synthesize a new target compound named GEM-ZZQ,and then we confirmed its chemical structure by n...
关键词：GEMCITABINE THIAZOLIDINONE H2O2-sensitive moiety non-small cell lung cancer 
Synthesis of Some New Spiro <i>β</i>-Lactams and Thiazolidinones Compounds Containing Sulfur Incorporating Quinon Compounds被引量：1
《International Journal of Organic Chemistry》2012年第4期352-361,共10页Nadia Ali Ahmed Elkanzi 
A series of spiro, β-Lactams, and thiazolidinones incorporating compounds 4 have been synthesized by cycloaddition reaction of, chloroacetyl chloride and mercaptoacetic acid with the synthesized Shiff,s bases 5a-c to...
关键词：Β-LACTAM SPIRO THIAZOLIDINONE Synthesized Cycloaddition 
Reaction of thiocarboxanilide derivatives of 2-phenylimino-3-phenyl-4-thiazolidinone and 1,3-diphenyl-2-thioxo-4-imidazolone with hydrazonoyl halides and active chloromethylene compounds被引量：1
《Natural Science》2011年第3期199-207,共9页Hamdi M. Hassaneen Omar A. Miqdad Nada M. Abunada Ahmad A. Fares 
The potassium salts of thiocarboxanilide of 2- phenylimino-3-phenyl-4-thiazolidinone and 1,3- diphenyl-2-thioxo-4-imidazolone react with hydrazonoyl halides in N,N-dimethylformamide to afford the corresponding 1,3,4-t...
关键词：Hydrazonoyl HALIDES 1 3 4-Thiadiazoline THIAZOLIDINONE 
Activation of G551D-CFTR by Bicyclooctane Compounds Is cAMP-dependent and Exhibits Low Sensitivity to Thiazolidinone CFTR Inhibitor CFTRinh-172
《Chemical Research in Chinese Universities》2005年第2期183-186,共4页WANGYing ZHAOLu HECheng-yan XULi-na YANGHong 
Start-upFundforReturnedOverseasScholarsfromNortheastNormalUniversity,NationalScienceFundforDistinguishedYoungScholars(No.30325011),DistinguishedYoungScholarsFundofJilinProvince(No.20030112),ExcellentYoungTeachersProgramofMinistryofEducation,P.R.China,theNationalNaturalScienceFoun-dationofChina(No.30470405)andtheNaturalScienceFoundationofJilinProvince(No.20010548and20030708).
The G551D-CFTR mutation causing cystic fibrosis(CF) results from a missense mutation at codon 551(G551D) in the gene encoding of the cystic fibrosis transmembrane conductance regulator(CFTR). The G551D mutation in CFT...
关键词：Cystic fibrosis(CF) Cystic fibrosis transmembrane conductance regulator(CFTR) Short circuit current analysis Pharmacological activation 
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