Synthesis of Some New Thioethers and 4-Thiazolidinones Bearing 3-(Pyridine-4'-yl)-1,2,4-Triazino[5,6-<i>b</i>]Indole Moiety as Antifungal Agents  

作　　者：Wafa A. Baker Bawazir 

机构地区：[1]Department of Chemistry, Faculty of Science, KAU, Jeddah, Saudi Arabia

出　　处：《International Journal of Organic Chemistry》2019年第1期37-46,共10页有机化学国际期刊（英文）

摘　　要：Some new asymmetric thioethers 5 and 4-thiazolidinones 6 have been obtained from condensation of 5-formyl-3-(pyridin-4'-yl)-1,2,4-triazino[5,6-b] indole (3) with halogenated aromatic amines followed by addition of thiophenol and/or cycloaddition with thiolactic acids in nonpolar solvents. Structures of the products confirmed by elemental analysis and spectral measurements. The new systems obtained were evaluated as antifungal agents.Some new asymmetric thioethers 5 and 4-thiazolidinones 6 have been obtained from condensation of 5-formyl-3-(pyridin-4'-yl)-1,2,4-triazino[5,6-b] indole (3) with halogenated aromatic amines followed by addition of thiophenol and/or cycloaddition with thiolactic acids in nonpolar solvents. Structures of the products confirmed by elemental analysis and spectral measurements. The new systems obtained were evaluated as antifungal agents.

关 键 词：THIOETHERS Thiazolidnones 1 2 4-Triazino INDOLE FUNGICIDAL Cycloaddition 

分 类 号：O6[理学—化学]