光学活性拆分剂脱氢枞胺的制备性纯化及其表征  

Purification and Characterization of Optically Active Resolving Reagent Dehydroabietylamine

作　　者：王道林[1] 牛之猛[1] 刘华东[1] 

机构地区：[1]北京理工大学化工与环境学院,北京100081

出　　处：《北京理工大学学报》2004年第4期357-359,共3页Transactions of Beijing Institute of Technology

基　　金：教育部留学回国人员科研启动基金

摘　　要：采用松香胺与对甲基苯磺酸成盐法,对光学活性拆分剂脱氢枞胺的纯化工艺进行了改进.通过对甲基苯磺酸与工业产品松香胺D在乙醇中形成脱氢枞胺、双脱氢枞胺、四脱氢枞胺的对甲基苯磺酸盐,经重结晶分离得到光学纯度的脱氢枞胺的对甲基苯磺酸盐,再利用碱游离得到光学纯度的脱氢枞胺.最后通过红外光谱、核磁共振光谱及高效液相色谱等对其进行表征.The purification process of dehydroabietylamine was improved, whereby the industrial rosin amine D was reacted with p -toluenesulfonic acid in ethanol to get a mixture of dehydro-abietylamine p -toluenesulfonate, didehydroabietylamine p -toluenesulfonate, and tetradehydro-abietylamine p -toluenesulfonate. The mixture was separated by recrystallization to get pure dehydroabietylamine p -toluenesulfonate. Then pure dehydroabietylamine was obtained by reacting dehydroabietylamine p -toluenesulfonate with sodium hydroxide. The structure of dehydro-abietylamine was characterized by IR ()~1HNMR and HPLC.

关 键 词：光学活性物质拆分剂 脱氢枞胺 松香胺D 对甲基苯磺酸 

分 类 号：O62[理学—有机化学]