268例心脏、心包肿瘤的病理分析  

Pathological Analysis of 268 Cases of Tumors in the Heart and the Pericardium

作　　者：宋一璇[1] 胡瑞德[1] 姚青松[2] 

机构地区：[1]中山大学病理教研室,广东广州510080 [2]广州市刑事科学技术研究所,广东广州510030

出　　处：《中山大学学报（医学科学版）》2003年第3期197-201,i002,共6页Journal of Sun Yat-Sen University:Medical Sciences

基　　金：国家自然科学基金(39170396)

摘　　要：【目的】研究心脏、心包的原发和继发性肿瘤的发病率和病种分布。【方法】对尸体解剖9588例、活体组织检查30万例资料进行回顾性研究。【结果】有原发性心脏、心包肿瘤64例,发病率0.14％。良性肿瘤55例(黏液瘤49例,89％;心包囊肿4例,7％;心包囊性淋巴管瘤及良性畸胎瘤各1例,共占3％),恶性肿瘤9例(心包间皮瘤3例,33％;血管内皮肉瘤及纤维肉瘤各2例,22％;未分化肉瘤和心包恶性畸胎瘤各1例,11％),良、恶性肿瘤之比为6:1。943例全身各脏器恶性肿瘤中心脏转移204例(22％),首位是白血病(55%),其后依次肺癌(14％)、恶性淋巴瘤(13％)、间叶组织肉瘤(5％)和胃癌(3%)。心脏、心包原发性瘤与继发性瘤之比为1:3。【结论】心脏、心包原发瘤发病率为0.14％,转移瘤22％,继发瘤是原发瘤的3倍。肝癌、绒癌、脑瘤及胰腺癌少见或不见心转移。[ Objective] To investigate the primary and secondary tumors of the heart and pepricardi-um. [Methods] 9 588 autopsies and 300 thousand biopsies were studied retrospectively. [Results] Sixty-four cases of primary and 204 cases of secondary heart tumors were discovered, revealing an incidence of 0. 14% and 2% , respectively. Among the primary tumors, there were 49 myxo-mas, 4 cysts of the pericardium , 3 mesotheliomas, 2 angiosarcomas and fibrosarcomas, 1 malignant teratoma and undifferentiated sarcoma, 1 cystic lymphangioma and teratoma of the pericardium. The rate of benign (55 cases) to malignant (9 cases) tumors in the heart was 6 : 1. For secondary tumors which involved the heart (including both metastatic and local extension), the most common tumors were leukemia(55% ), carcinoma of the lung(14% ), lymphoma( 13% ), interstitial sarcoma (5% ) and cancer of stomach (3% ). The rate of primary cardiac tumors to metastatic cardiac tumors in the heart was 1 : 3. [Conclusions] The incidence of primary cardiac tumors was 0. 14% . The cardiac involvement in patients with malignancies is 22% . The incidence of Secondary cardiac tumors is 3 times more than that of primary cardiac tumors. The hemogenous metastasis is the most common way in secondary cardiac tumors. Interestingly hepatocarcinomas and choriocarcinomas were rarely metastasized in the heart. Non metastatic tumors in the heart were found in pancreatic carcinomas and brain tumors

关 键 词：心脏肿瘤 心包肿瘤 肿瘤病理学 发病率 病种分布 

分 类 号：R732.1[医药卫生—肿瘤]