氮化钛涂层对牙科合金析出金属离子的影响  

Effect of Titanium Nitride Coating on the Element Release from Ni-Cr and Co-Cr Alloys

作　　者：周雅彬[1] 米乃元[1] 李彦[1] 滕伟[1] 范丹妮[1] 

机构地区：[1]中山大学光华口腔医学院.附属口腔医院,广东广州510055

出　　处：《中山大学学报（医学科学版）》2003年第3期295-297,302,共4页Journal of Sun Yat-Sen University:Medical Sciences

摘　　要：【目的】评价氮化钛涂层对牙科Ni-Cr、Co-Cr合金在人工唾液中析出金属离子的影响。【方法】采用多弧离子镀法在临床上常用的Ni-Cr、Co-Cr合金表面沉积厚约2.5μm、均匀致密的氮化钛涂层,将涂层前后的合金置于37℃ 10 mL人工唾液中,分别于第3、15和60天收集合金浸渍液。采用电感耦合高频等离子体发射光谱分析法(JCP-AES)测定人工唾液中不同时间段析出的各类金属离子的量及成分并与涂层前相比。【结果】Ni-Cr、Co-Cr合金析出高水平金属离子,并随浸泡时间的延长而显著增加,析出的各类金属离子中,除Cr外,以Ni、Be、Mo等金属离子的析出量最为明显。经氮化钛涂层的Ni-Cr、Co-Cr合金析出的金属离子的总量及各类离子的浓度均较低,随着浸泡时间的延长,析出离子的量只有轻微的增加。涂层前后合金析出的各类金属离子的量(Cr除外)相比较,差异具有显著性(P<0.001)。【结论】氮化钛涂层可降低贱金属合金析出金属离子的量,提高合金的生物相容性。[Objective] To evaluate the effect of titanium nitride coating on the element quantities released from the Ni-Cr and Co-Cr alloys. [Methods] A thickness of 2, 5 μm TiN coating was coated to the surfaces of two commonly used alloys, the Ni-Cr and Co-Cr alloys, by multi-arc TiN coating technique. Then Ni-Cr alloy, Co-Cr alloy, TiN/Ni-Cr and TiN/Co-Cr were soaked individually in 10 mL sterile artificial saliva at 37μ for 3, 15 and 60 days respectively before artificial saliva was collected. Inductively coupled plasma atomic emission spectrophotometer(ICP-AES) was used to measure the quantities of elements released from every sample, including Ni, Cr, Co, Be, Mo, Ti and so on. The amount of total and each element released from the coated samples were compared with those uncoat-ed. Data were converted to μg of element released per cm2. [Results] The Ni-Cr and Co-Cr alloys released high levels of elements, including Ni, Be, Mo, but not Cr. The coated samples showed dramatically decrease compared with that of uncoated except Cr ( P < 0.001). The metal element levels, especially Ni and Be, released from those uncoated samples were greatly increased with the test time; while the amount of elements (except Cr) released from those coated only exhibited slight elevation. [Conclusion] Titanium nitride coating can decrease the element release from the Ni-Cr and Co-Cr alloys. This indicates that titanium nitride coating may improve the biocompatibility of non-precious alloys.

关 键 词：氮化钛涂层 牙科材料 合金 金属离子 多弧离子镀法 生物相容性 

分 类 号：R783.1[医药卫生—口腔医学]