皮质类固醇性青光眼40例临床分析  

Corticoteroid glaucoma in 40 cases

作　　者：陈璐[1] 

机构地区：[1]中国广东暨南大学医学院深圳眼科中心,518001

出　　处：《国际眼科杂志》2004年第2期282-284,共3页International Eye Science

摘　　要：目的:探讨皮质类固醇性青光眼的临床特征及防治方法。方法:资料完整的40例68眼患者的病史、皮质类固醇使用情况、临床特征及诊治过程作回顾性分析。结果:40例(68眼)患者,男26例(65%),<40岁31例(78%),大多数患者连续使用浓度较高的地塞米松复合制剂,临床表现类似开角型青光眼,半数以上双眼视盘及视野改变不一致。随访6mo～5a,停用皮质类固醇眼药,眼压恢复正常42眼(62%),依赖降眼压眼药控制眼压7眼(10%),抗青光眼手术后眼压恢复正常19眼(28%)。治疗后视力提高52眼(76%),视野改善45眼(66%)。结论:皮质类固醇性青光眼多发生于男青年,临床表现类似开角型青光眼。皮质类固醇升眼压作用与所用激素的种类、浓度和剂量有关。临床应用皮质类固醇药物应密切监控眼压。确诊后早期治疗,视功能改变是可逆的。AIM: To study the clinical features, prevention and treatment of corticoteroid glaucoma.· METHODS: A total of 40 cases (68 eyes) of corticoteroid glaucoma were chosen and their history, corticosteroid administration, diagnosis and treatment were reviewed.· RESULTS: Among the 40 cases, 65% patients were male, and 77.5% were younger than 40 years old. The clinical manifestations were similar to those of open angle glaucoma. During the follow-up of 6m-5a, intraocular pressure returned to normal in 42 eyes (62%) when corticoteroid administration was stopped, was controlled in 7 eyes (10%) by administrating antiglaucoma drop, and returned to normal in 19 eyes (28%) after surgery. Finally, the visual acuity increased in 52 eyes (76%) and the visual field improved in 45 eyes (66%).· CONCLUSION: Corticoteroid glaucoma occurs mainly to young male patients. The IOP raising ability of corticoteroid is associated with the type, concentration and dose of the hormone used. IOP should be closely monitored when corticoteroid is used, and early treatment can make visual function recover. ·

关 键 词：皮质类固醇性青光眼 临床特征 皮质类固醇 眼压 

分 类 号：R775[医药卫生—眼科]