钠-氨水体系对ω-酰基莰烯的还原反应研究  

Study on the Reduction of ω-Acylcamphene with Sodium in Aguous Ammonia

作　　者：李艳霞[1] 温红丽[2] 付长清[2] 王幸聪[2] 肖转泉[2] 

机构地区：[1]江西农业大学理学院,江西南昌330045 [2]江西师范大学化学学院,江西南昌330027

出　　处：《江西师范大学学报（自然科学版）》2004年第2期132-135,共4页Journal of Jiangxi Normal University(Natural Science Edition)

基　　金：江西省自然科学基金资助项目(972036).

摘　　要：以钠-氨水体系为还原剂,苯为溶剂,对属于α,β-不饱和酮类的8个ω-酰基莰烯类化合物进行了还原.结果表明:足量钠作用下,还原产物为饱和醇(α-异莰烷基醇),有内型与外型两种异构体;酰基部分的烃基越大,外型醇的比例越高.对所得的α-异莰烷基醇作了GC-MS分析,对还原过程与立体化学进行了讨论.Eight ω-acylcamphene compounds belonging to α,β-unsaturatable ketone were reduced with sodium in aguous ammonia in benzene solvent.The results indicated that:the reduced products were saturated alcohol (α-isocamphanyl alcohol)under the use of enough sodium,which have two isomers:endo-configuration and exo-configuration,and that if having the bigger the alkyl of acyl part than exo-alcohol product was of the higher the proport.The products were analyzed by GC-MS,while the reduction process and stereochemistry discussed.

关 键 词：ω-酰基莰烯 还原反应 立体化学 GC-MS 钠-氨水体系 香料 

分 类 号：TQ655[化学工程—精细化工] O621.254.2[理学—有机化学]