新生儿和婴幼儿闪光视透发电位  

Flash visual evoked potentials on newborns and infants

作　　者：张微[1] 戚以胜[1] 李平余 郭玉銮[3] 董砚儒[3] 施锦娜[3] 尹素英[4] 林倩[5] 聂文英[5] 宫露霞[5] 

机构地区：[1]北京市耳鼻咽喉科研究所首都医科大学附属北京同仁医院临床听力中心,100005 [2]美国纽约Mount Sinai医学中心眼科 [3]北京大学附属首钢医院眼科 [4]北京大学附属积水潭医院眼科 [5]济南市妇幼保健院济南市新生儿听力筛查康复中心

出　　处：《中华医学杂志》2004年第2期111-114,共4页National Medical Journal of China

基　　金：国家自然科学基金资助项目 (3 0 10 0 2 0 7)

摘　　要：目的　探究闪光视诱发电位 (FVEP)应用于新生儿和婴幼儿视功能检查的可行性 ,获得正常新生儿和婴幼儿FVEP结果 ,为眼病筛查未通过的小儿及高危新生儿的进一步视功能诊断作参考。方法　　应用美国Nicolet公司的Viking -IV诱发电位仪对 4 1例正常新生儿 (日龄≤ 4d)和 18例 1月龄至 5月龄的婴幼儿进行FVEP检测。结果　分别得到新生儿组和婴幼儿组FVEP各波潜伏期参考值 ,以及左右眼潜伏期差别的正常范围参考值 ,发现FVEP各波潜伏期随年龄增长有缩短的趋势 ;闪光刺激频率对FVEP结果影响有显著意义 (P <0 0 5 )。结论　FVEP的主波P1潜伏期稳定可靠 ,将其作为主要参考值应用于新生儿和婴幼儿视功能检查是可行的 ,但在临床应用此方法时 ,一定要参照不同年龄段的FVEP值。Objective To explore the feasibility of applying flash visual evoked potentials (FVEPs) for visual function test newborns and infants and bring out the consultable laboratory values of FVEPs.The technology of FVEP could be used as diagnostic tests for those who failed the screening and the infants who were cared for in the NICU.Methods 41normal neonates(≤4 days) and 18 normal infants (≤5 months) were tested with FVEP by Nicolet Viking-IV model evoked potentials apparatus.Results Get the normal reference range of FVEPs latency in both groups and the consulting value of the difference between the left and right eyes.It has been observed from the paper that the latency of FVEPs has the tendency to shorten with the age increasing.It also shows that there are extreme significant changes of FVEPs ( P <0.05) by different frequency of stimulating light.Conclusion The latency of FVEPs P1 is steady and could be applied to newborns-infants visual function test.While,the references of FVEPs according to different age group should be taken into account when we using this measure in clinic.

关 键 词：新生儿 婴幼儿 闪光视诱发电位 视功能检查 大脑皮质功能 

分 类 号：R770.4[医药卫生—眼科]