超声循环提取灵芝中三萜类化合物的研究  

Study on ultrasonic circulation technique to extraction of triterpenoids from Ganoderma lucidum

作　　者：黄书铭[1] 杨新林[1] 张自强[1] 徐建兰 朱鹤荪[3] 

机构地区：[1]北京理工大学生命科学与技术学院,北京100081 [2]无锡市三联高科技开发有限公司,江苏无锡214023 [3]北京理工大学材料科学研究中心,北京100081

出　　处：《中草药》2004年第5期508-510,共3页Chinese Traditional and Herbal Drugs

基　　金：国家重点科技项目 (攻关 )计划

摘　　要：目的　研究超声循环技术在灵芝中三萜类化合物提取中的应用。方法　在常规提取方法的基础上 ,增加超声循环的处理步骤。结果　通过试验对比 ,超声循环提取所需各种溶剂用量减少 ,提取时间缩短 ,目的产物提取率提高了 4 0 %。与常规方法提取得到的目的产物之间存在着良好的相关性。结论　超声循环技术用于灵芝中三萜类化合物的提取具有良好的应用前景。ObjectTo study the application of ultrasonic circulation technique for the extraction of triterpenoids from Ganoderma lucidum (Leyss.ex Fr.) Karst. Methods On the basis of conventional method, the processing steps of ultrasonic circulation treatment were added. Results The comparative experiments showed that less amounts of various solvents and shorter extraction time were needed for ultrasonic circulation extraction, with the product ratio of about 40 percent higher than that of conventional method. Furthermore, a good consistency of the target product analyzed by HPLC was found between two different extraction methods. Conclusion The ultrasonic circulation technique has a potential application to the extraction of triterpenoids from G. lucidum.

关 键 词：灵芝 三萜类化合物 超声循环技术 高效液相色谱 

分 类 号：R284.2[医药卫生—中药学] R286.02[医药卫生—中医学]