大鼠脊髓中神经生长因子受体TrkA的表达与分布  

Expression and distribution of nerve growth factor receptor TrkA in rat spinal cord

作　　者：王永刚[1] 张勇[1] 张骐[1] 吴爱群[2] 何成[1] 

机构地区：[1]第二军医大学神经生物学教研室 [2]第二军医大学解剖学教研室,上海200433

出　　处：《郑州大学学报（医学版）》2004年第3期421-422,共2页Journal of Zhengzhou University(Medical Sciences)

基　　金：上海市科学技术发展基金资助项目 0 1JC14 0 0 4;军队医学杰出人才基金资助项目 0 1J0 11

摘　　要：目的 :检测神经生长因子受体TrkA在大鼠脊髓中的表达与分布。方法 :通过Westernblot检测TrkA在脊髓中的表达 ;通过免疫荧光组织化学 ,利用激光共聚焦显微镜检测TrkA在神经元中的定位。结果与结论 :TrkA广泛分于脊髓各层神经元及灰质内 。Aim: To study the expression and distribution of nerve growth factor receptor TrkA in rat spinal cord. Methods:Western blot and fluorescent immunohistochemistry were used to test the expression and distribution of TrkA in rat spinal cord. The distribution pattern was observed under laser confocal microscope. Result and Conclusion: TrkA was expressed and distributed ubiquitously in both eytoplasm and dendrites of spinal cord.

关 键 词：TRKA 脊髓 神经生长因子 受体 大鼠 

分 类 号：R742[医药卫生—神经病学与精神病学]