睾丸生殖细胞肿瘤病理形态及免疫组化研究  

PATHOLOGY AND IMMUNOHISTOCHEMISTRY OF TESTICULAR GERM CELL TUMORS——A report of 100 cases

作　　者：李涤臣[1] 曹光群[1] 葛霞[1] 承泽龙[1] 章可仪[1] 周序珑 陶仪声[1] 

机构地区：[1]蚌埠医学院病理学教研室

出　　处：《蚌埠医学院学报》1992年第1期6-8,F004,共4页Journal of Bengbu Medical College

摘　　要：本文回顾复习100例睾丸生殖细胞肿瘤。分析各亚型的病理形态特征。卵黄囊瘤可有肝样、卵黄囊样、宫内膜样、乃至肠样分化;疏松的空状结构、透明小球(PAS染色阳性)有助于与胚胎性癌相鉴别。免疫过氧化物酶标记,keratin和CEA对诊断有一定意义。β—HCG是绒癌和胚胎性癌中合体滋养细胞的特异性标记。精原细胞瘤也可表达异位β—HCG。One hundred cases of testicular germ cell tumors were reviewed pathologically and imnaunohistoc hemically.It was found that yolk sac tumors would show hepatoid, yolk sac-like, endometrioid, and intestine-like features of differentiation. The presence of a pattern of loose vacuolated network and hyaline globules is very helpful in the differential diagnosis from embryonal carcinoma. Im-munoPeroxidase studies were carried out with antibodies to keratin, CEA, and β-HCG. Keratin and CEA studies were significant in the diagnosis. β-HCG app ears to be a specific marker for syncytial trophoblasts in choriocarcinoma and embryonal carcinoma.Ectopic β-HCG might be expressed in seminoma.

关 键 词：睾丸 精原细胞瘤 卵黄囊瘤 病理 

分 类 号：R737.210.2[医药卫生—肿瘤]