先天性巨细胞病毒感染对婴幼儿智力及听力的影响  

Effect of congenital cytomegalovirus infection on infant's intelligence and hearing

作　　者：罗丽茹[1] 陈享[1] 冼珊[1] 郑健梅[1] 

机构地区：[1]广东肇庆市第一人民医院儿保中心,526021

出　　处：《中国基层医药》2004年第4期408-409,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的　探讨先天性巨细胞病毒 (HCMV)感染对婴幼儿智力及听力的影响。方法　对 10 2例先天性HCMV感染儿及 92例非感染儿于 6个月、1岁、4岁对智力、听力进行随访对比。结果　感染组智力落后 16例 (DQ) ,对照组 3例 (DQ) ,感染组明显高于对照组 (P <0 0 1) ;BAEP测试 ,6个月至 4岁随访 ,感染组听力异常 2 4例 (2 7耳 ) ,对照组 3例 (5耳 ) ,两组差异有显著意义 (P <0 0 1)。结论　先天性HCMV感染对婴幼儿的智力及听力有明显影响 ,应随访监测 ,及早干预。Objective To explore the effect of congenital human cytomegalovirus(HCMV) infection on infant's intelligence development and hearing.Methods 102 neonates with congenital HCMV infection and 96 uninfected neonates were measured of their intelligence and hearing.They were followed up by 6 months,one year and four years.Results Sixteen infants had low DQ in infected group,but only 3 infants in the uninfected group(P<0.01).BAEP testing showed:24 infected infants(27 ears) compared with 3 uninfected infants(5 ears) had hearing impairment.The difference between the two groups was significant(P<0.01).Conclusion Congenital HCMV has effects on infant's intelligence and hearing and follow up and early intervention must be carried out.

关 键 词：先天性巨细胞病毒感染 婴幼儿 智力 听力 非遗传性感音神经性耳聋 

分 类 号：R174[医药卫生—妇幼卫生保健]