急性脑梗死患者血浆D-二聚体测定的临床意义  

The clinical significance of plasma d-dimer measurement for patients with acute cerebral infarction

作　　者：陈润成[1] 刘玉春[1] 

机构地区：[1]深圳市龙岗区人民医院神经内科,广东深圳518172

出　　处：《黑龙江医药科学》2004年第3期28-29,共2页Heilongjiang Medicine and Pharmacy

摘　　要：目的 :了解急性脑梗死患者血浆 D-二聚体 (D- Dimer)含量的变化 ,为进一步研究急性脑梗死病理生理机制 ,病程判定及疗效观察提供试验依据。方法 :对 71例急性脑梗死患者和 6 4例正常人用双抗体夹心 (Elisa)法检测血浆 D-二聚体含量。结果 :急性期脑梗死患者较正常人血浆 D-二聚体含量明显增高 ,恢复期下降 ,急性期和恢复期比较有显著差异。结论 :提示急性脑梗死是高凝状态的表现 ,血浆 D-二聚体测定可作为急性期脑梗死病程判定及疗效观察的有用指标。Objective:To understand the change of plasma d-dimer content, to study the pathophysiologic mechanisms in patients with acute cerebral infarction and to provide the proof for judging course and efficaly. Methods:We measured the plasma content of d-dimer by Elisa in 71 patients with acute cerebral infarction and 64 healthy persons. Results: The plasma content of the patients' d-dimer was higher than that in healthy persons in acute stage and decreased in convalescence, with significant difference in two stages. Conclusion:The results indicated that acute cerebral infarction was the manifestation of hyper coagulation.The content of plasma d-dimer was an useful index for judging the course of acute cerebral infarction and observing the efficacy.

关 键 词：脑梗死 D-二聚体 

分 类 号：R743.33[医药卫生—神经病学与精神病学]