酒渣鼻与蠕形螨和细菌感染的关系  

Relationship between the Demodex and Bacteria Infection in Human Rosacea

作　　者：胡群[1] 王焱[2] 佟立[3] 

机构地区：[1]内蒙古民族大学医学院人体寄生虫学教研室,通辽028041 [2]内蒙古民族大学医学院组织胚胎学教研室,通辽028041 [3]内蒙古民族大学附属医院皮肤科,通辽028066

出　　处：《中国寄生虫学与寄生虫病杂志》2004年第1期50-53,共4页Chinese Journal of Parasitology and Parasitic Diseases

摘　　要：目的　了解酒渣鼻与人体蠕形螨感染和细菌感染的关系 ,以及治疗酒渣鼻的有效药物和方法。　方法　对确诊的 2 60例酒渣鼻患者 ,用透明胶带法检查两侧鼻沟处和面部皮损处感染的蠕形螨 ,显微镜检查蠕形螨感染情况 ,用手术刀片刮取鼻部和面部皮损处皮脂和组织进行培养 ,染色后显微镜检查细菌感染情况。洗净面部后将自制的“祛渣洗剂”药液涂于患处 ,每天早、晚各 1次 ,连用 7d为 1疗程 ,治疗效果分为痊愈、显效、好转及无效。　结果　 2 60例酒渣鼻患者中细菌感染者 2 0 9例 ,占 80 4% (其中 10 1例细菌感染者为伴随真菌感染 )。蠕形螨感染者 193例 ,占74 2 %。在 2 0 9例细菌感染者中 193例为细菌和蠕形螨混合感染 ,占细菌感染者的 92 3 %。随着蠕形螨感染阳性率的上升细菌感染阳性率也上升 ,表明蠕形螨感染与细菌感染密切相关。治疗效果 :“祛渣洗剂”的疗效指数为 <3 0 %。平均总有效率为 73 5 % ,红斑期疗效好于丘疹脓疱期和鼻赘期。　结论　蠕形螨感染后长期寄生于毛囊和皮脂腺内 ,使皮肤组织病理改变是导致酒渣鼻的主要致病原因 ,继而引起的细菌继发感染是使酒渣鼻的病程延长 ,病情加重的重要因素之一。Objective To understand the relationship between Demodex and bacteria infection in rosacea (brandy nose), and to find effective means for the treatment. MethodsCellophane tape was used to detect Demodex on the nasolabial grooves and the face; sebum and tissue on face was scraped and cultured to examine bacteria under microscope. The hospital_made anti_rosacea lotion was used on the affected part two times a day for 7 days. Results It was found that 193 (74^2%) of 260 cases with rosacea were infected by Demodex and 209 (80^4%) of the patients were infected by bacteria. The overall effective rate of the treatment for rosacea was 73^5%. Conclusion Bacteria infection in rosacea is an important factor inducing rosacea. The curative effect of the anti_rosacea lotion is good.

关 键 词：酒渣鼻 蠕形螨 细菌感染 透明胶带法 细菌培养 

分 类 号：R757.3[医药卫生—皮肤病学与性病学]