结膜松弛症的组织病理学观察  

The analysis of histopathology of conjunctivochalasis

作　　者：张兴儒[1] 蔡瑞霞[2] 王宝华[2] 李青松[1] 刘晔翔[1] 许琰[1] 

机构地区：[1]上海中医药大学普陀临床医学院眼科,200062 [2]上海中医药大学普陀临床医学院病理科,200062

出　　处：《中华眼科杂志》2004年第1期37-39,共3页Chinese Journal of Ophthalmology

摘　　要：目的　观察结膜松弛症组织病理学的改变。方法　对病变组 17例结膜松弛症患者松弛结膜组织和对照组 15例单纯白内障患者球结膜组织 ,采用苏木精 伊红染色、Verhoeff弹力纤维染色、Masson三色染色和Mallory磷钨苏木素染色方法。对照观察两组组织病理改变。结果　结膜松弛症患者结膜组织表现为结膜鳞状上皮增生 ,角化不全 ,基底细胞疏密不等的色素沉着 ,固有层间质出血 ,弹力纤维减少。结论　结膜松弛症患者的松弛结膜组织发生了结膜上皮增生 ,弹力纤维减少及慢性炎性病变等病理改变。弹力纤维的减少可能是本病的主要发病原因之一。 (中华眼科杂志 ,2 0 0 4,40 :3 7 3 9)Objective To observe the his topathological change of conjunctivochalasis Methods Conjunctival tissue was collected from 17 patients with conjunctivochalasis and 15 simple cataract patients. By HE/Verhoeff elastic fiber staining, the histopathological changes of conjunctival tissues in the patients were compared with those of simple cataract patients. Results The pathologic changes in conjunctivochalasis patients were characterized with hyperplasia of squamous epithelium with parakeratosis, pigmentation with different level in basal cell, hemorrhage, edema of stroma, infiltration of lymphocyte and plasmocyte. The elastic fiber layer was decreased. Conclusion There was hyperplasia of conjunctival epithelium, decrease of elastic fiber and chronic inflammation in patients with conjunctivochalasis. The decrease of elastic fiber should be considered as major cause of the changes of conjunctiva. (Chin J Ophthalmol, 2004,40: 37-39)

关 键 词：结膜松弛症 组织病理学 发病机制 手术方法 

分 类 号：R777.3[医药卫生—眼科]