食管癌淋巴结转移的临床病理因素分析  

Clinical and Pathological Relative Factors Analysis on Lymph Nodes Metastasis of Thoracic Esophagus Carcinoma

作　　者：伊斯刊达尔 帕丽达[1] 王海峰[1] 阿合力[1] 张瑾熔[1] 许素玲[1] 

机构地区：[1]新疆医科大学附属肿瘤医院放疗二科,乌鲁木齐市830011

出　　处：《中国肿瘤临床》2004年第10期584-586,共3页Chinese Journal of Clinical Oncology

摘　　要：探讨食管癌淋巴结转移的临床病理相关因素。方法:对326例食管癌根治性手术病例进行统计,分析各主要临床病理改变与淋巴结转移的关系。结果:326例食管癌中淋巴结转移149例,转移率为45.7%。病变长度≤3cm、3.1～5cm、5.1～7cm、7.1～9cm和>9cm的淋巴结转移率分别为28.6%、30.1%、51.4%、65.5%和73.7%。组织学类型中低分化、中分化、高分化鳞癌,鳞腺癌、腺癌的淋巴结转移率分别为87.0%、34.0%、14.3%、57.1%和62.5%。浸润深度T1、T2、T3、T4的淋巴结转移率分别为13.3%、29.9%、47.8%和92.6%。以上三种因素间比较均有显著性差异(P<0.001)。淋巴结转移率与性别、年龄、民族、肿瘤部位和病理大体类型的关系不大。病变长度与浸润深度呈正相关。结论:肿瘤越大(长),浸润越深,分化程度越低,易发生淋巴结转移。Objective: To explore the lymphatic metastasis clinical and pathological relative factors of esophagus carcinoma. Methods: To analyze the relativity between clinical and pathological factors and factors of 326 patients with esophagus carcinoma underwent radical esophagectomy. Results: 149 patients had lymph nodes metastasis in 326 patients with esophagus carcinoma. Rate of lymph nodes metastasis was 45.7%. Rate of lymph nodes metastasis was 28.6%, 30.1%, 51.4%, 65.5% and 73.7% for the length of lesion ≤3cm, 3.1～5cm, 5.1～7cm, 7.1～9cm and >9cm. Rate of lymph nodes metastasis was 87.0%, 34.0%, 14.3%, 57.1% and 62.5% respectively for low differentiation, middle differentiation, high squamous cell carcinoma, squamous- adenocarcinoma and adenocarcinoma. Rate of lymph nodes metastasis was 13.3%, 29.9%, 47.8% and 92.6% respectively for T1, T2, T3 and T4. There was statistic remarkability between three above factors. There was obvious relativity between rate of lymph nodes metastasis and sex, age, nationality, site of tumor and pathological types. There was positive relativity between length of lesion and depth of tumor invasion. Conclusion: The longer carcinoma and the deeper invasion with lower differentiation, the more lymph nodes metastasis.

关 键 词：食管癌 淋巴结转移 病理 分析 

分 类 号：R735.1[医药卫生—肿瘤]