临床应用重组SARS病毒双抗原夹心诊断试剂盒的检测效果评价  

Evaluation of the Clinical Detection Results Using Recombinant SARS Antigen-Capturing ELISA Diagnostic Kit

作　　者：刘萱[1] 李平[1] 石玉玲[2] 易艳萍[1] 任冽[1] 匡铁吉[3] 段昭辉[4] 王云龙 马清钧[1] 曹诚[1] 

机构地区：[1]军事医学科学院生物工程研究所,北京100850 [2]广州军区广州总医院,广州510010 [3]中国人民解放军第309医院,北京100084 [4]中山大学附属第二医院,广州510000 [5]河南省生物工程技术研究中心,河南450003

出　　处：《病毒学报》2004年第2期172-174,共3页Chinese Journal of Virology

摘　　要：It is necessary to establish a rapid and accurate diagnostic method for controlling the epidemic of severe acute respiratory syndrome (SARS). Cooperating with Henan Bioengineering Research Center, we developed a new diagnostic kit for antibodies to SARS virus based on antigen-capturing ELISA. Here we report the clinical detection results obtained from several hospitals which used this diagnostic kit for SARS diagnosing. Comparing with other detection kits now used, the antigen-capturing ELISA has stronger specificity and higher sensitivity, and more fits for rapid confirming and diagnosing of SARS cases, SARS epidemiological investigation and SARS epidemic source research.It is necessary to establish a rapid and accurate diagnostic method for controlling the epidemic of severe acute respiratory syndrome (SARS). Cooperating with Henan Bioengineering Research Center, we developed a new diagnostic kit for antibodies to SARS virus based on antigen-capturing ELISA. Here we report the clinical detection results obtained from several hospitals which used this diagnostic kit for SARS diagnosing. Comparing with other detection kits now used, the antigen-capturing ELISA has stronger specificity and higher sensitivity, and more fits for rapid confirming and diagnosing of SARS cases, SARS epidemiological investigation and SARS epidemic source research.

关 键 词：严重急性呼吸综合征 SARS 病毒 双抗原夹心法 诊断试剂盒 血清标本 

分 类 号：R373.9[医药卫生—病原生物学] R446.61[医药卫生—基础医学]