Diagnosis and Treatment of Chromophobe Cell Renal Carcinoma （Report of 3 cases）  

作　　者：XiaopingQi KaoXingLin ZhenjiangLi XiaofengHuang XiaowenDai 

机构地区：[1]DepartmentofUrology,117thHospitalofPLA,Hangzhou310013,China. [2]ElectronmicroscopyCenterof4thMilitaryMedicalUniversity,China.

出　　处：《Chinese Journal of Clinical Oncology》2004年第1期58-62,共5页中国肿瘤临床（英文版）

摘　　要：OBJECTIVE To study the diagnosis and treatment of chromophobe cell renal carcinoma (CCRC). METHODS Three cases of CCRC were studied by analyzing the results of an operation, by light microscopy, immunohistochemistry, Hale's colloidal iron staining and electronmicroscopy (EMC). RFESULTS Doppler ultrasonic and CT features were not specific. Histopathology: Grossly the tumor tissue was homogeneous, light brown in color with central necrotic foci; Light microscopy: Macrocyte, fine reticular cytoplasm with clear cell border; Hale's colloidal iron staining: positive; positive EMA, CK19, vimentin, Ckpan, and negative S-100; EMC: numerous intracyto-plasmic membranous small cysts. All patients were followed up for 14.1-31 months (19.7 months on average), one patient had lung metastasis 11 months after resection of a G,~ tumor, two alive patients had no local recurrences and metastases. CONCLUSIONS CCRC is histo-pathologically, immunohistochemically and electron microscopically distinct from other renal cancers. Surgical tumor removal is the best way for treatment. It is probably a type of cancer with low malignant potential and favorable prognosis.

关 键 词：诊断 治疗 肾细胞癌 组织病理学 手术疗法 

分 类 号：R737.11[医药卫生—肿瘤]