核素骨显像诊断肿瘤骨转移的临床价值  

Clinical value of radionuclide bone scintigraphy in diagnosis of skeletal metastases in patients with carcinoma

作　　者：刘长江[1] 刘秀芊[1] 苏敏[1] 杨建[1] 肖亚景[1] 

机构地区：[1]广东医学院附属医院同位素科,广东湛江524001

出　　处：《河北医学》2004年第5期387-390,共4页Hebei Medicine

摘　　要：目的 :分析各类肿瘤骨转移的特点和规律 ,探讨核素骨显像诊断肿瘤骨转移的临床价值。方法 :对 4 6 2例肿瘤患者静脉注射99m Tc -MDP 1110MBq行SPECT全身骨显像 ,并对结果分析。结果 :①肿瘤骨转移阳性结果 :肺癌阳性率 4 4.9% ,乳腺癌阳性率 33.3% ,鼻咽癌阳性率 5 6 .0 % ,前列腺癌阳性率 6 2 .5 % ,消化道肿瘤阳性率 2 4 .5 % ,其他肿瘤阳性率 2 1.4 %。②肿瘤转移部位以脊柱、肋骨、骨盆最为多见。③肿瘤转移灶骨显像多为“热”区病灶。④肿瘤转移率与病程有关。结论 :核素骨显像对肿瘤的早期诊断、疾病分期、治疗方案的选择、预后评估有重要的价值。Objective:To investigate the clinical value of radionuclide bone scintigraphy in diagnosis of skeletal metastases in patients with carcinoma. Methods:462 patients with carcinoma were injected intravenously 99m Tc-MDP 1110MBq and performed the whole body imaging.Results:①The positive rate in patients with lung cancer, breast cancer, nasopharyngeal carcinoma, prostate cancer, gastrointestinal carcinoma and otehers was 44.9%, 33.3%, 56.0%, 62.5, 24.5% and 21.4% respectively. ②Frequent sites for metastatic bone scintigraphy lesions were the spine, pelvic bone and ribs. ③Most of bone metastases showed 'hot' spots. ④The rate of metastatas was related with course of carcinoma. Conclusion: Radionuclide bone scintigraphy has important clinic values for patients with carcinoma in early diagnosis, malignant tumor staging,treatment and response to therapy.

关 键 词：骨显像 骨转移 SPECT 

分 类 号：R730.43[医药卫生—肿瘤]