电刺激小脑顶核改善脑损害致意识障碍的临床疗效观察  

Clinical research of fastigial nucleus electrical stimulation in treatment of disorders of consciousness by brain damage

作　　者：杨军[1] 董为伟[1] 钟世江[2] 

机构地区：[1]重庆医科大学临床学院神经病学研究所,重庆400016 [2]山东济宁医学院附属医院神经内科,山东272100

出　　处：《重庆医科大学学报》2004年第3期383-385,共3页Journal of Chongqing Medical University

摘　　要：目的 :研究电刺小脑顶核 (FNS)改善脑损害引起的不同程度意识障碍的临床疗效 ,结合文献探讨其可能机制。方法 :9例不同病因所致脑损害意识障碍患者 ,经常规治疗加用FNS ,观察其对意识状况 (GCS评分 )、脑电图 (EEG)改善情况。结果 :FNS治疗后患者意识水平明显改善。结论 :FNS能够改善脑损害导致的意识障碍 ,提示该方法可能有神经保护和促醒作用。Objective:To investigate the clinical effect of fastigial nucleus electrical stimulation(FNS) treating the disorders of consciousness by brain damage,and explore the possible mechanism.Methods:9 patients with the disorders of consciousness by brain damage of different pathogeneses were studied.They were treated with FNS on the basis of routine medical treatment.And Glasgow Coma Scale (GCS),electroencephalogram(EEG) and the clinical effects were observed.Results:After FNS treatment,the level of conciousness was improved.GCS were increased 5.22±1.44,which showed significant difference compared to that before treatment ( P <0.001).Moreover, EEG was also improved.Conclusion:The results demonstrate that FNS can improve the disorders of consciousness by brain damage,which may be related to its clinical efficacy in neuroprotection and awakening.

关 键 词：电刺激 小脑顶核 意识障碍 脑损害 

分 类 号：R743.3[医药卫生—神经病学与精神病学]