脑膜瘤^(99)Tc^m-MIBI与^(99)Tc^m ECD SPECT脑显像的对照研究  

Brain SPECT with ^(99)Tc^m-MIBI and ^(99)Tc^m-ECD:a comparative study in imaging characteristics of meningioma

作　　者：宋锦宁[1] 张芬茹[2] 刘守勋[1] 王茂德[1] 胡国瑛[2] 

机构地区：[1]西安交通大学第一医院神经外科,陕西西安710061 [2]西安交通大学第一医院核医学科,陕西西安710061

出　　处：《中国医学影像技术》2004年第5期768-770,共3页Chinese Journal of Medical Imaging Technology

摘　　要：目的　探讨脑膜瘤99Tcm MIBI和99Tcm ECDSPECT脑显像的影像特征 ,并评价其应用价值。方法　对 10例正常对照者及 18例脑膜瘤患者进行99Tcm MIBI和99Tcm ECDSPECT脑显像 ;分析病灶的影像特征。结果　正常对照者99Tcm MIBI显像脑实质内均无核素浓聚 ;99Tcm ECD显像脑实质内放射性核素分布大致均匀 ,左右侧基本对称。 18例脑膜瘤99Tcm MIBI显像见肿瘤处均表现为均匀的圆形或卵圆形放射性核素浓聚 ,其阳性率为 10 0 % ;而99Tcm ECD显像 18例中有 17例示肿瘤处表现为形态规整、边缘整齐的圆形或卵圆形内凹缺损 ,其形态与99Tcm MIBI显像所示的浓聚区相吻合 ,另1例为假阴性结果 ,其阳性率为 94.4%。结论　99Tcm MIBI结合99TcmObjective To study the imaging characteristics of meningioma using brain SPECT with 99 Tc m MIBI and 99 Tc m ECD, and to evaluate their application value in diagnosis of meningioma. Methods Ten normal controls and 18 patients of meningiomas were performed with 99 Tc m MIBI and 99 Tc m ECD rCBF tomographic brain imaging, and imaging characteristics of meningioma were analyzed. Results In normal controls, 99 Tc m MIBI imaging showed no radioactive distribution in brain grey matter; 99 Tc m ECD rCBF imaging showed homogeneous and symmetrical radioactive distribution throughout the grey matter. In 18 of 18 patients, a homogeneous round or oval accumulation of radioactivity in meningioma area was found with 99 Tc m MIBI SPECT imaging. Positive rate with 99 Tc m MIBI was 100%.In 17 of 18 patients, 99 Tc m ECD rCBF imaging showed round or oval concave defects with smooth contour in the cerebral cortex tumor area. The defect shape and position in 99 Tc m ECD image was corresponding to the accumulation area in 99 Tc m MIBI image. One patient was false negative in 99 Tc m ECD image. Positive rate with 99 Tc m ECD was 94.4%. Conclusion The combined use of 99 Tc m MIBI and 99 Tc m ECD SPECT brain imaging is useful in diagnosis of meningioma.

关 键 词：脑膜瘤 放射性核素显像 甲氧基异丁基异腈 双半胱乙酯 

分 类 号：R739.41[医药卫生—肿瘤] R817.4[医药卫生—临床医学]